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Gene Page - CG Number : CG10446
Gene Summary - CG10446:

CG10446: The gene similar to Deadpan is referred to in FlyBase by the symbol Dmel\Side (CG10446, FBgn0032741). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: DNA binding. Based on sequence similarity, it is predicted to be involved in the biological process: regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Helix-loop-helix domain; Orange. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 06-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages.

Gene summary for CG10446 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10446:CG10446 is not perturbed in primary screen.
CG10446 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10446.
Cell Count:
CG_NumberCategoryR1R2R3
CG10446Primary screen596630241
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10446:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191189-0.4800871480.757475483-0.079197602-0.3568905980.3302632221.1363595040.2814006961.820453508-0.2265957710.726682178-0.4635846140.128708047-0.73443036-0.4263297130.074459143-0.059836786-2.123040793-1.628320656-2.479783842-0.3051109840.794976329-0.307868983-0.314553556
192970.179855617-0.318257552-0.3721719250.5770462650.8621184591.0164833370.7164223190.9029099871.704501011.0154972071.5115602710.8140738151.7125461641.214678738-0.5517326911.505045092.0782835381.6863290281.9623228111.761464793-0.3216137821.1136377660.637273803
193247-0.4657320411.8370594961.204628725-0.432901293-0.3207463790.2144658070.857550283-0.0207970680.1250944670.328082487-0.386019161-0.190278597-0.254933017-0.003905267-0.314641638-0.5812508270.119796084-0.147792397-0.095098584-0.0630883540.152166092-0.7380183460.444532311
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10446 is not tested in classification assay
Integrated Annotations for CG10446 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
negative regulation of transcription from RNA polymerase II promoterGO:0000122inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853
regulation of transcription, DNA-dependent
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred by curator from GO:0003677
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
DNA bindingGO:0003677inferred from sequence or structural similarity with MGD:Hes1; MGI:MGI:104853
Other annotations
DatabaseLink
FlyBaseClick here to see CG10446 in FlyBase
FLIGHTClick here to see CG10446 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10446 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10446
Entrez GeneEntrez Gene page for CG10446
UniprotUniprot page for CG10446

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)