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Gene Page - CG Number : CG10459
Gene Summary - CG10459:

CG10459: This gene is referred to in FlyBase by the symbol Dmel\CG10459 (FBgn0033440). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: receptor binding. Based on sequence similarity, it is predicted to be involved in the biological process: negative regulation of transforming growth factor beta receptor signaling pathway. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: G-protein beta WD-40 repeat; WD40 repeat; WD40 repeat, conserved site; WD40-repeat-containing domain; WD40/YVTN repeat-like-containing domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected. Peak expression observed during early pupal stages.

Gene summary for CG10459 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10459:CG10459 is not perturbed in primary screen.
CG10459 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10459.
Cell Count:
CG_NumberCategoryR1R2R3
CG10459Primary screen8841380
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10459:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191193-0.3834336131.5068747743.198773937-0.112334020.574886922.9362048286.2742814172.3713576073.9996407841.0126246482.582016189-0.2257227420.9813848710.905440461.037901613-0.3360135472.9372396614.767936213.048785125.671371426-0.4131015279.1524438645.949862404
19293-0.514672065-1.629223629-0.407309139-2.376944462-2.949855268-1.479367426-1.866343053-1.927445707-4.094798025-1.326860682-1.655351714-0.468431221-1.708841781-1.086744849-0.49393397-3.328479707-2.210650093-2.437897143-2.678459885-4.133966319-0.655497984-3.533772606-4.303791552
193243-0.100582365-0.0710040530.472109201-0.294842011.408221391.6748420392.7326526451.2292088861.5167423950.5400827440.719622185-0.7716823690.6254858760.6974527982.165306230.7416489440.898381430.2927367750.8404825881.811687023-0.379598383-0.1488703420.398971462
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10459 is not tested in classification assay
Integrated Annotations for CG10459 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
negative regulation of transforming growth factor beta receptor signaling pathwayGO:0030512inferred from sequence or structural similarity with MGD:Strap; MGI:MGI:1329037
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cellular_componentGO:0005575no biological data available
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
receptor bindingGO:0005102inferred from sequence or structural similarity with MGD:Strap; MGI:MGI:1329037
Other annotations
DatabaseLink
FlyBaseClick here to see CG10459 in FlyBase
FLIGHTClick here to see CG10459 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10459 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10459
Entrez GeneEntrez Gene page for CG10459
UniprotUniprot page for CG10459

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)