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Gene Page - CG Number : CG10460
Gene Summary - CG10460:

CG10460: The gene crammer is referred to in FlyBase by the symbol Dmel\cer (CG10460, FBgn0034443). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: cysteine-type endopeptidase inhibitor activity. There is experimental evidence that it is involved in the biological process: short-term memory; long-term memory. 9 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Proteinase inhibitor I29, cathepsin propeptide. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of moderate expression. Peak expression observed during early pupal stages.

Gene summary for CG10460 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10460:CG10460 is perturbed in following parameters in primary screen: Fmph2
CG10460 is perturbed in following parameters in classification assay (fluid): LP_Fint4- NuFluct+(fld) Rto3- SP_Fmph2- SP_Fmph3-
CG10460 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10460.
Cell Count:
CG_NumberCategoryR1R2R3
CG10460Primary screen694295330
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10460:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191194-0.3599073342.815145924.349989931-0.61213899-0.0002996211.7963135753.7504348951.2187026222.4013619920.219852474-0.2795044420.9384793031.9111727312.3343249870.8138340370.2972024751.4264602022.6108463551.9102443463.069831120.6173700576.3719066313.337950419
192920.0262134022.6628004481.0857771660.148877098-0.2154928060.322838661.092498133-0.3904349531.1983564212.5213861551.5144117621.6242454352.1920556981.705789772-0.6112942210.7229647384.5593654272.9907180793.1229178361.350095001-0.626525034-0.538237336-0.835262184
1932422.127983590.8418724761.462139373-0.8063162260.6357663781.5761940483.9276524240.8918837591.2375740760.3957268821.093873433-0.1850256952.6378166190.7361447811.3083078020.2168224740.6620480670.3189974840.5736673021.7520867090.066733949-0.2792218640.075575533
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10460Slide19C0.1151.2181.7251.286
CG10460Slide19O0.2471.4521.0531.110
CG10460Slide19P0.6211.0131.1040.997
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG10460 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
long-term memoryGO:0007616inferred from mutant phenotype
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
cysteine-type endopeptidase inhibitor activityGO:0004869inferred from direct assay
Other annotations
DatabaseLink
FlyBaseClick here to see CG10460 in FlyBase
FLIGHTClick here to see CG10460 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10460 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10460
Entrez GeneEntrez Gene page for CG10460
UniprotUniprot page for CG10460

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)