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Gene Page - CG Number : CG10463
Gene Summary - CG10463:

CG10463: This gene is referred to in FlyBase by the symbol Dmel\CG10463 (FBgn0032819). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: tRNA dihydrouridine synthase activity; zinc ion binding; nucleic acid binding; flavin adenine dinucleotide binding. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: oxidation-reduction process; tRNA processing. 3 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: Aldolase-type TIM barrel; Zinc finger, CCCH-type; tRNA-dihydrouridine synthase; tRNA-dihydrouridine synthase, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages.

Gene summary for CG10463 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10463:CG10463 is not perturbed in primary screen.
CG10463 is perturbed in following parameters in classification assay (fluid): LP_Fint1+ Rto2+ Rto3+ SP_Fint1+ SP_Fint2+
CG10463 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10463.
Cell Count:
CG_NumberCategoryR1R2R3
CG10463Primary screen8461122461
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10463:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191197-0.33698197-0.2394710970.215498292-0.1524724351.519890434-0.637922765-0.832444603-0.700589385-0.471944877-0.613274217-0.417413752-0.744229067-0.376747422-0.5649571470.675310832-0.068262311-1.23769862-0.411492923-1.824479457-0.163520401-0.2603985277.8119766584.088241861
1921192.1703879672.6343206942.7079910394.1101570915.156020137.2890353741.6911239975.061496745-0.5460172384.3508607041.4139845620.502608164-0.418580568-0.1609497732.2794893221.20681753.5450832840.1157807532.58095558-1.0219522135.930835943-3.533772606-4.303791552
1932690.0278159650.5037933641.104046773-0.8267106691.7491414493.0706716365.2676044151.9266799352.6790062312.0192921931.200679073-0.0219229862.9466042442.327567615-0.3089802931.5112586511.8163647841.6997736691.7226802883.1838634661.3885420450.94565911-0.196096459
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10463Slide8C0.1831.4151.0991.097
CG10463Slide8O0.1271.1451.0161.105
CG10463Slide8P0.1221.6961.2591.195
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG10463 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
oxidation-reduction processGO:0055114inferred from electronic annotation with InterPro:IPR001269, InterPro:IPR018517
tRNA processing
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
flavin adenine dinucleotide bindingGO:0050660inferred from electronic annotation with InterPro:IPR001269, InterPro:IPR018517
zinc ion binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10463 in FlyBase
FLIGHTClick here to see CG10463 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10463 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10463
Entrez GeneEntrez Gene page for CG10463
UniprotUniprot page for CG10463

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)