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Gene Page - CG Number : CG10472
Gene Summary - CG10472:

CG10472: This gene is referred to in FlyBase by the symbol Dmel\CG10472 (FBgn0035670). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: serine-type endopeptidase activity. It is reported to be involved in the biological process: proteolysis. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Peptidase S1/S6, chymotrypsin/Hap; Peptidase S1/S6, chymotrypsin/Hap, active site; Peptidase S1A, chymotrypsin-type; Peptidase cysteine/serine, trypsin-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of very low expression. Peak expression observed during late larval stages.

Gene summary for CG10472 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10472:CG10472 is perturbed in following parameters in primary screen: Fmph2
CG10472 is perturbed in following parameters in classification assay (fluid): NuCellD+(fld) NuCirc+(fld) NuSize-(fld) Okt+(fld)
CG10472 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10472.
Cell Count:
CG_NumberCategoryR1R2R3
CG10472Primary screen740392434
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10472:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191203-0.393604518-0.2814456840.711874791-0.313054281.0324297760.8545073940.2267158650.604690403-1.716784343-1.0581785910.370539722-0.6088005190.2840146990.834528295-0.493638168-0.154915277-2.098166267-1.55903148-0.76085329-2.060218709-0.2929006386.216391623.143652232
192113-0.1779916120.255804780.877471183-0.362649277-0.0616290081.1454772483.3175045881.124348421.5117058180.2277777030.9789365930.1581164620.750680250.597515832-0.2703538280.0492442411.6143887122.5178473211.2268992161.655372712-0.4908817070.4576724820.013296394
1932631.7882115951.4092074120.943582794-0.15934281.5797830443.043080474.136566741.7761116422.2426980351.666975722.0398001990.9976423892.652990111.5244427250.6271462061.1693072391.6661220360.9872402471.7581346892.6083350610.350307355-0.29128157-0.121701601
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10472Slide19C0.4800.9421.1151.146
CG10472Slide19O0.0701.2761.0761.176
CG10472Slide19P0.1231.0901.0411.150
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG10472 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
proteolysisGO:0006508non-traceable author statement
proteolysis
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
serine-type endopeptidase activityGO:0004252non-traceable author statement
serine-type endopeptidase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10472 in FlyBase
FLIGHTClick here to see CG10472 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10472 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10472
Entrez GeneEntrez Gene page for CG10472
UniprotUniprot page for CG10472

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)