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Gene Page - CG Number : CG10474
Gene Summary - CG10474:

CG10474: This gene is referred to in FlyBase by the symbol Dmel\CG10474 (FBgn0034427). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Peptidase T2, asparaginase 2. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected. Peak expression observed during early larval stages.

Gene summary for CG10474 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10474:CG10474 is perturbed in following parameters in primary screen: Fmph2
CG10474 is perturbed in following parameters in classification assay (fluid): LP_Fclc- NuCellD+(fld) NuCirc+(fld) NuSize-(fld) Rto1- SP_Fclc- SP_Fmph1- SP_Fmph2- SP_Fmph3- SP_Fnum-
CG10474 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10474.
Cell Count:
CG_NumberCategoryR1R2R3
CG10474Primary screen847549535
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10474:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191205-0.4419389351.1121350661.7683190790.2737165771.659707872.8063822134.0271447071.7459297753.5610131480.8005471163.134857875-0.8219962021.0163858780.46623007-0.495090866-0.028373412.7164167585.0711358452.4246725865.218574371.1376205014.1154486933.320161673
192111-0.4144487580.0195298440.33614958-0.0253003050.6604240541.1366525191.7089620820.91521921.1969707410.2450789310.582909803-0.0403463650.9857055780.7809435640.021438550.2538103120.4441476490.3707830780.3315210781.477141439-0.073016950.005333194-0.429217819
193261-0.404634013-0.000510209-0.1611768830.0485324011.7099520642.2178070714.4803679332.0523210572.437475390.6018195780.721437998-0.5930226941.9754696121.5997428291.9170658851.5409334120.9262168230.4169805681.2642542262.43480266-0.3470956190.3589710741.241535591
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10474Slide19C0.1891.3631.0511.735
CG10474Slide19O0.2351.4841.3390.963
CG10474Slide19P0.1061.1331.1021.346
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG10474 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
-
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
N4-(beta-N-acetylglucosaminyl)-L-asparaginase activityGO:0003948inferred from sequence or structural similarity with UniProtKB:O02467
Other annotations
DatabaseLink
FlyBaseClick here to see CG10474 in FlyBase
FLIGHTClick here to see CG10474 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10474 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10474
Entrez GeneEntrez Gene page for CG10474
UniprotUniprot page for CG10474

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)