Home Browse SearchHelp DownloadGroup

.:: RNAiDB - Gene Page ::.
Gene Page - CG Number : CG10478
Gene Summary - CG10478:

CG10478: The gene α Karyopherin-4 is referred to in FlyBase by the symbol Dmel\αKap4 (CG10478, FBgn0035657). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: protein transmembrane transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process: protein import into nucleus. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: 26S proteasome non-ATPase regulatory subunit 5; Armadillo; Armadillo-like helical; Armadillo-type fold; Importin subunit alpha. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed at stages throughout the pupal period, in adult male stages.

Gene summary for CG10478 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10478:CG10478 is not perturbed in primary screen.
CG10478 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10478.
Cell Count:
CG_NumberCategoryR1R2R3
CG10478Primary screen624332244
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10478:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191209-0.7807638330.8013376580.388282877-0.228955062-0.4961118990.8294317712.8114401640.9596030172.6670722550.9039690164.1152707530.5775620440.1300561680.0391732682.172540290.5010088553.2043949197.5968963894.2048783923.073050158-0.3944816844.4644075091.311174922
1921070.011434777-0.3481693251.2504482510.143617188-0.0573916951.2763361682.3040533660.6886434651.3832442140.8537623040.6353823690.0317340611.0882975530.917939806-0.1818896210.0792925341.5170037581.8056098731.4875812051.526519479-0.574926323-0.519075835-0.590181937
19325714.35525568.2909895344.3394067384.284856097-0.0271354230.9764656024.7098040240.0148251690.506850469-0.021550423-2.0976675010.184384191-0.9944683941.0471324050.483047853-0.398873395-1.36672599-0.538663788-1.1169202311.005631413-0.9409949270.0543612811.881990766
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10478 is not tested in classification assay
Integrated Annotations for CG10478 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
protein import into nucleusGO:0006606inferred from sequence or structural similarity with HGNC_gene:KPNA4; HGNC:6397; OMIM:6029702
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nuclear poreGO:0005643inferred from sequence or structural similarity with HGNC_gene:KPNA4; HGNC:6397; OMIM:6029702
cytoplasm
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
protein transmembrane transporter activityGO:0008320inferred from sequence or structural similarity with HGNC_gene:KPNA4; HGNC:6397; OMIM:6029702
protein binding involved in protein folding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10478 in FlyBase
FLIGHTClick here to see CG10478 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10478 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10478
Entrez GeneEntrez Gene page for CG10478
UniprotUniprot page for CG10478

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)