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Gene Page - CG Number : CG10488
Gene Summary - CG10488:

CG10488: The gene eyegone is referred to in FlyBase by the symbol Dmel\eyg (CG10488, FBgn0000625). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: RNA polymerase II regulatory region sequence-specific DNA binding. There is experimental evidence that it is involved in the biological process: notum development; eye development; antennal development; eye-antennal disc development; compound eye development; negative regulation of transcription from RNA polymerase II promoter; compound eye morphogenesis. 56 alleles are reported. The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: organ system subdivision; adult segment; organ system; imaginal precursor; adult; thoracic segment; external compound sense organ; multicellular structure; eo support cell; salivary gland imaginal ring. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Homeobox, conserved site; Homeodomain; Homeodomain-like; Paired domain; Winged helix-turn-helix transcription repressor DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 06-12 hour embryonic stages, during early pupal stages.

Gene summary for CG10488 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10488:CG10488 is not perturbed in primary screen.
CG10488 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10488.
Cell Count:
CG10488Primary screen57324226
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10488:
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10488 is not tested in classification assay
Integrated Annotations for CG10488 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
eye developmentGO:0001654inferred from mutant phenotype
compound eye morphogenesis
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
transcription factor complexGO:0005667inferred from sequence or structural similarity with MGD:Pax3; MGI:MGI:97487
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
sequence-specific DNA binding transcription factor activityGO:0003700inferred from sequence or structural similarity with MGD:Pax3; MGI:MGI:97487
sequence-specific DNA binding transcription factor activity
Other annotations
FlyBaseClick here to see CG10488 in FlyBase
FLIGHTClick here to see CG10488 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10488 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10488
Entrez GeneEntrez Gene page for CG10488
UniprotUniprot page for CG10488

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)