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Gene Page - CG Number : CG10491
Gene Summary - CG10491:

CG10491: The gene vein is referred to in FlyBase by the symbol Dmel\vn (CG10491, FBgn0003984). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: heparin binding; epidermal growth factor receptor binding. There is experimental evidence for 12 unique biological process terms, many of which group under: system development; appendage development; multicellular organismal development; post-embryonic organ morphogenesis; biological regulation; cellular process; instar larval or pupal morphogenesis; positive regulation of cell proliferation; cellular component organization or biogenesis; localization; cell fate commitment; digestive tract development; notum development. 64 alleles are reported. The phenotypes of these alleles are annotated with 43 unique terms, many of which group under: organ system subdivision; organ system; adult segment; thoracic segment; non-connected developing system; imaginal precursor; embryonic/larval hypodermal muscle; sense organ; portion of tissue; embryonic/larval neuron; external compound sense organ. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: EGF-like, conserved site; Epidermal growth factor-like domain; Immunoglobulin I-set; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed at stages throughout embryogenesis, during late pupal stages.

Gene summary for CG10491 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10491:CG10491 is not perturbed in primary screen.
CG10491 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10491.
Cell Count:
CG_NumberCategoryR1R2R3
CG10491Primary screen649200108
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10491:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191218-0.0425723422.3256067932.0287677160.3195518730.1194141660.7128631551.4995590261.1685190281.4961897021.2276473411.8970357070.2361284590.511299758-0.1914587461.4556222880.6100093360.6772078343.0056303250.8575664821.7506406350.5335643662.102703574-0.036741114
192681.2893628821.382773966-0.2041888950.491220374-0.712308088-1.232954776-1.298989261-0.683959665-1.337055943-0.59915623-0.619812651-0.6620297090.39873121-0.333579399-0.221937991-0.528665844-0.376198834-0.664814311-1.048976843-1.086109492-0.748877093-0.403254316-0.790955526
1932180.030743865-0.413433954-0.142570352-0.01529407-2.196855547-1.55746876-1.275661565-2.140074626-2.3376600021.0142757070.573938091-0.143613548-1.454510148-1.038850485-0.391722173-0.228581688-1.279840851-0.689115778-2.063465013-2.96716193-0.016336839-0.4822062691.211197845
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10491 is not tested in classification assay
Integrated Annotations for CG10491 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
epidermal growth factor receptor signaling pathwayGO:0007173inferred from mutant phenotype
notum cell fate specification
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
extracellular regionGO:0005576non-traceable author statement
extracellular region
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
epidermal growth factor receptor bindingGO:0005154inferred from mutant phenotype
epidermal growth factor receptor binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10491 in FlyBase
FLIGHTClick here to see CG10491 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10491 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10491
Entrez GeneEntrez Gene page for CG10491
UniprotUniprot page for CG10491

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)