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Gene Page - CG Number : CG10493
Gene Summary - CG10493:

CG10493: The gene PH domain leucine-rich repeat protein phosphatase is referred to in FlyBase by the symbol Dmel\Phlpp (CG10493, FBgn0032749). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein serine/threonine phosphatase activity. There is experimental evidence that it is involved in the biological process: protein dephosphorylation. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Leucine-rich repeat; Protein phosphatase 2C-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression. Peak expression observed within 06-18 hour embryonic stages, during late pupal stages.

Gene summary for CG10493 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10493:CG10493 is perturbed in following parameters in primary screen: Fmph2 NuSize
CG10493 is perturbed in following parameters in classification assay (fluid): CellSize+(fld) LP_Fint1+ LP_Fint2+ LP_Fint3+ LP_Fint4+ LP_Fmph1+ LP_Fmph3+ NuCellD-(fld)
CG10493 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10493.
Cell Count:
CG10493Primary screen973311141
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10493:
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG10493 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
protein dephosphorylationGO:0006470non-traceable author statement
protein dephosphorylation
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cellular_componentGO:0005575no biological data available
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
protein serine/threonine phosphatase activityGO:0004722non-traceable author statement
protein serine/threonine phosphatase activity
Other annotations
FlyBaseClick here to see CG10493 in FlyBase
FLIGHTClick here to see CG10493 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10493 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10493
Entrez GeneEntrez Gene page for CG10493
UniprotUniprot page for CG10493

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)