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Gene Page - CG Number : CG10497
Gene Summary - CG10497:

CG10497: The gene Syndecan is referred to in FlyBase by the symbol Dmel\Sdc (CG10497, FBgn0010415). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: transmembrane signaling receptor activity. There is experimental evidence that it is involved in the biological process: motor neuron axon guidance; energy homeostasis; detection of light stimulus involved in visual perception; positive regulation of gene silencing by miRNA; regulation of multicellular organismal metabolic process; axon guidance; epithelial cell migration, open tracheal system. 69 alleles are reported. The phenotypes of these alleles are annotated with: dorsal branch; medulla; muscle fiber; presumptive embryonic/larval central nervous system; abdominal segmental nerve; lamina plexus; synapse; lateral transverse muscle. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Neurexin/syndecan/glycophorin C; Syndecan. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages.

Gene summary for CG10497 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10497:CG10497 is not perturbed in primary screen.
CG10497 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10497.
Cell Count:
CG10497Primary screen509202175
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10497:
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10497 is not tested in classification assay
Integrated Annotations for CG10497 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
axon guidanceGO:0007411inferred from mutant phenotype
detection of light stimulus involved in visual perception
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
plasma membraneGO:0005886inferred from sequence or structural similarity with RGD:Sdc1; RGDID:3648
plasma membrane
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
transmembrane signaling receptor activityGO:0004888inferred from sequence or structural similarity with EMBL:U41760; protein_id:AAB81325
cytoskeletal protein binding
Other annotations
FlyBaseClick here to see CG10497 in FlyBase
FLIGHTClick here to see CG10497 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10497 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10497
Entrez GeneEntrez Gene page for CG10497
UniprotUniprot page for CG10497

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)