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Gene Page - CG Number : CG10498
Gene Summary - CG10498:

CG10498: The gene cdc2c is referred to in FlyBase by the symbol Dmel\cdc2c (CG10498, FBgn0004107). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: cyclin-dependent protein kinase activity. There is experimental evidence that it is involved in the biological process: cellular process; JAK-STAT cascade. 26 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine- / dual-specificity protein kinase, catalytic domain; Serine/threonine-protein kinase, active site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages, in adult female stages.

Gene summary for CG10498 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10498:CG10498 is not perturbed in primary screen.
CG10498 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10498.
Cell Count:
CG_NumberCategoryR1R2R3
CG10498Primary screen37419191
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10498:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
1912230.207414195-0.9286231750.958375879-0.434523676-0.608234959-0.5209657440.043629348-0.730290788-0.9443691190.526898061-0.047529295-0.1161776260.7324454160.471318330.66428257-0.6091696621.522111044-0.5443069630.749936326-1.171934059-0.8592153634.1663971150.652334416
19263-0.5653248080.1617839240.8951304922.6879749098.4195256065.030852953-1.4543601151.806820815-1.793093369-1.5448830020.4602170990.231735891-0.7540079770.641123677-0.1594502639.2473961131.759873991-0.7709008110.98598605-2.1876485474.282624544-3.533772606-4.303791552
1932135.611535144.7068459935.0552484971.0954300241.1681096591.2458503954.1113936390.661135541-2.1062667250.249861753-0.4063281090.3227608580.1686312-0.728219718-0.563160739-0.664894941.1515060320.540807344-1.532706793-1.591799313-0.316392438-0.325520026-0.43172547
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10498 is not tested in classification assay
Integrated Annotations for CG10498 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
G1/S transition of mitotic cell cycleGO:0000082inferred from sequence or structural similarity inferred from sequence or structural similarity with SGD_LOCUS:CDC28; SGD:S000000364
G2/M transition of mitotic cell cycle
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
microtubule associated complexGO:0005875inferred from direct assay
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
protein serine/threonine kinase activityGO:0004674non-traceable author statement
cyclin-dependent protein kinase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10498 in FlyBase
FLIGHTClick here to see CG10498 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10498 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10498
Entrez GeneEntrez Gene page for CG10498
UniprotUniprot page for CG10498

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)