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Gene Page - CG Number : CG10501
Gene Summary - CG10501:

CG10501: The gene α methyl dopa-resistant is referred to in FlyBase by the symbol Dmel\amd (CG10501, FBgn0000075). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: carboxy-lyase activity; deaminase activity. There is experimental evidence that it is involved in the biological process: chitin-based cuticle development; catecholamine metabolic process. 49 alleles are reported. The phenotypes of these alleles are annotated with: anal pad; cuticle; anal slit. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Aromatic-L-amino-acid decarboxylase; Pyridoxal phosphate-dependent decarboxylase; Pyridoxal phosphate-dependent transferase, major domain; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, major region, subdomain 2; Pyridoxal-phosphate binding site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 12-18 embryonic stages.

Gene summary for CG10501 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10501:CG10501 is not perturbed in primary screen.
CG10501 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10501.
Cell Count:
CG_NumberCategoryR1R2R3
CG10501Primary screen5641297402
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10501:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191224-0.788746283-0.4089159062.089593636-0.443936753-0.4616491480.7727385522.8859408360.7200773912.3401967731.9357971842.119173411-0.3721171852.5682595681.5438276940.266961023-0.2791419712.6938485264.3046201961.1737519883.4425178570.3023818415.1518476822.100877828
192621.9807793123.1955164561.7820432384.76918397215.418127446.0404206142.7478645274.291156439-0.6907286852.6275264361.7273180132.127284475-0.580199974-0.4324462853.09380034421.623431123.1185717350.4769625753.153602097-0.8796134545.884416334-3.533772606-4.303791552
193212-0.701183268-0.226510597-0.02046764-0.4589874591.2142458161.8655878273.7763259611.421467682.157336371.3078550272.8748688910.6766924871.2371605221.0606734491.843012251.8474364571.8862945762.2448018321.631503363.0861077410.241579747-0.60930664-0.019563247
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10501 is not tested in classification assay
Integrated Annotations for CG10501 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
catecholamine metabolic processGO:0006584non-traceable author statement
chitin-based cuticle development
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cellular_componentGO:0005575no biological data available
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
aromatic-L-amino-acid decarboxylase activityGO:0004058inferred from sequence or structural similarity with EMBL:AF071068
carboxy-lyase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10501 in FlyBase
FLIGHTClick here to see CG10501 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10501 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10501
Entrez GeneEntrez Gene page for CG10501
UniprotUniprot page for CG10501

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)