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Gene Page - CG Number : CG10505
Gene Summary - CG10505:

CG10505: This gene is referred to in FlyBase by the symbol Dmel\CG10505 (FBgn0034612). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ATPase activity, coupled to transmembrane movement of substances; transporter activity. There is experimental evidence that it is involved in the biological process: response to zinc ion; response to copper ion. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: AAA+ ATPase domain; ABC transporter, conserved site; ABC transporter, integral membrane type 1; ABC transporter, transmembrane domain; ABC transporter, transmembrane domain, type 1; ABC transporter-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed during late larval stages.

Gene summary for CG10505 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10505:CG10505 is not perturbed in primary screen.
CG10505 is perturbed in following parameters in classification assay (fluid): LP_Fclc- LP_Fint2- LP_Fint3- LP_Fmph1- LP_Fmph2- LP_Fmph3- LP_Fnum- NuFluct-(fld) NuSize-(fld) Okt+(fld) Rto1+ Rto2+ SP_Fclc- SP_Fint3- SP_Fmph2- SP_Fmph3-
CG10505 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10505.
Cell Count:
CG10505Primary screen5291219506
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10505:
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG10505 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
response to zinc ionGO:0010043inferred from genetic interaction with MTF-1
response to copper ion
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
ATP-binding cassette (ABC) transporter complexGO:0043190inferred from sequence or structural similarity with EMBL:AF071202
integral to membrane
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
ATPase activity, coupled to transmembrane movement of substancesGO:0042626inferred from sequence or structural similarity with EMBL:AF071202
transporter activity
Other annotations
FlyBaseClick here to see CG10505 in FlyBase
FLIGHTClick here to see CG10505 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10505 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10505
Entrez GeneEntrez Gene page for CG10505
UniprotUniprot page for CG10505

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)