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Gene Page - CG Number : CG10522
Gene Summary - CG10522:

CG10522: The gene sticky is referred to in FlyBase by the symbol Dmel\sti (CG10522, FBgn0002466). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: diacylglycerol binding; protein serine/threonine kinase activity. There is experimental evidence that it is involved in the biological process: cytokinesis after mitosis; chromatin organization; regulation of cytokinesis, actomyosin contractile ring assembly; cytokinesis; cytokinesis, completion of separation; cytokinesis, actomyosin contractile ring assembly; regulation of actin cytoskeleton organization. 24 alleles are reported. The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system; multicellular structure; anatomical structure; external compound sense organ; adult; organ system subdivision; organelle; cell part; sense organ; non-connected developing system; imaginal precursor; nucleus. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: AGC-kinase, C-terminal; Citron-like; Protein kinase C-like, phorbol ester/diacylglycerol binding; Protein kinase, ATP binding site; Protein kinase, C-terminal; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine- / dual-specificity protein kinase, catalytic domain; Serine/threonine-protein kinase, active site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages.

Gene summary for CG10522 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10522:CG10522 is not perturbed in primary screen.
CG10522 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10522.
Cell Count:
CG10522Primary screen563238385
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10522:
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10522 is not tested in classification assay
Integrated Annotations for CG10522 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
cytokinesisGO:0000910inferred from mutant phenotype
cytokinesis after mitosis
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
actomyosin contractile ringGO:0005826inferred from direct assay
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
protein serine/threonine kinase activityGO:0004674non-traceable author statement
diacylglycerol binding
Other annotations
FlyBaseClick here to see CG10522 in FlyBase
FLIGHTClick here to see CG10522 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10522 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10522
Entrez GeneEntrez Gene page for CG10522
UniprotUniprot page for CG10522

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)