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Gene Page - CG Number : CG10535
Gene Summary - CG10535:

CG10535: The gene Elongator complex protein 1 is referred to in FlyBase by the symbol Dmel\Elp1 (CG10535, FBgn0037926). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: phosphorylase kinase regulator activity. There is experimental evidence that it is involved in the biological process: RNA interference. 3 alleles are reported. The phenotype of these alleles is annotated with: trichogen cell. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: IKI3; Six-bladed beta-propeller, TolB-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early larval stages, in adult female stages.

Gene summary for CG10535 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10535:CG10535 is not perturbed in primary screen.
CG10535 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10535.
Cell Count:
CG_NumberCategoryR1R2R3
CG10535Primary screen673620142
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10535:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191238-0.3943534092.5143299422.498360041-0.0400803950.6916969290.7893223862.028325391.2121461261.740538887-0.0520461630.0422273820.043308676-1.266866002-0.078593872-0.210933037-0.1548251440.4373723960.231934730.7735146322.5051065620.9083659720.5860915532.348019444
192780.0630123110.3989124590.2973585910.0262463370.7566194420.5252471531.7175214590.4979923771.082711573-0.0837275460.4346082710.8066766431.0066817170.695314545-0.6853922570.3056737980.4804105590.5305865260.400820411.4771651030.332198886-0.012940168-0.621618047
1932286.0991247733.681968970.0762529350.182371497-1.604830387-1.711342488-0.446044163-1.840162975-1.8379317650.031253176-0.215761231-0.2131130540.9646794360.339811157-0.435098102-1.458597465-1.042561216-1.218589228-1.702063108-2.5096193140.809069744-0.9190392760.858696723
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10535 is not tested in classification assay
Integrated Annotations for CG10535 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
defense responseGO:0006952non-traceable author statement
signal transduction
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cytoplasmGO:0005737inferred from sequence or structural similarity with UniProtKB:O95163
transcription elongation factor complex
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
phosphorylase kinase regulator activityGO:0008607inferred from sequence or structural similarity with UniProtKB:O95163
Other annotations
DatabaseLink
FlyBaseClick here to see CG10535 in FlyBase
FLIGHTClick here to see CG10535 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10535 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10535
Entrez GeneEntrez Gene page for CG10535
UniprotUniprot page for CG10535

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)