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Gene Page - CG Number : CG10538
Gene Summary - CG10538:

CG10538: The gene CdGAPr is referred to in FlyBase by the symbol Dmel\CdGAPr (CG10538, FBgn0032821). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: GTPase activator activity. There is experimental evidence that it is involved in the biological process: retinal ganglion cell axon guidance. 15 alleles are reported. The phenotype of these alleles is annotated with: embryonic/larval optic stalk. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Rho GTPase activation protein; Rho GTPase-activating protein domain; Src homology-3 domain; Variant SH3. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period.

Gene summary for CG10538 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10538:CG10538 is not perturbed in primary screen.
CG10538 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10538.
Cell Count:
CG10538Primary screen533563223
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10538:
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10538 is not tested in classification assay
Integrated Annotations for CG10538 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
retinal ganglion cell axon guidanceGO:0031290inferred from mutant phenotype
signal transduction
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
intracellularGO:0005622inferred from electronic annotation with InterPro:IPR000198, InterPro:IPR008936
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
GTPase activator activityGO:0005096inferred from sequence or structural similarity
GTPase activator activity
Other annotations
FlyBaseClick here to see CG10538 in FlyBase
FLIGHTClick here to see CG10538 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10538 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10538
Entrez GeneEntrez Gene page for CG10538
UniprotUniprot page for CG10538

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)