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Gene Page - CG Number : CG1056
Gene Summary - CG1056:

CG1056: The gene Serotonin receptor 2 is referred to in FlyBase by the symbol Dmel\5-HT2 (CG1056, FBgn0087012). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: G-protein coupled amine receptor activity; serotonin receptor activity. There is experimental evidence that it is involved in the biological process: germ-band extension. 16 alleles are reported. The phenotypes of these alleles are annotated with: gastrula embryo; extended germ band embryo; pole cell; embryonic epidermis; ventral midline; denticle belt. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: GPCR, rhodopsin-like; GPCR, rhodopsin-like, 7TM. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed during late pupal stages.

Gene summary for CG1056 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG1056:CG1056 is perturbed in following parameters in primary screen: Tmph2
CG1056 is not tested in classification assay (fluid).
CG1056 is perturbed in following parameters in classification assay (transferrin): Fclc- Fint3- Fnum- Okt-(tfr) Rto1-(tfr) Rto2-(tfr) Rto3-(tfr) Tint1- Tint2- Tint3-
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG1056.
Cell Count:
CG1056Primary screen415492126
CG1056Secondary assay855602685
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG1056:
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Transferrin:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
F=Fdex; O=Surface TfR (Okt9); T=Tf

Integrated Annotations for CG1056 :Gene Ontology Annoations: Biological Process
Gene Ontology Annoations: Cellular Component
Gene Ontology Annoations: Molecular Function
Other annotations
FlyBaseClick here to see CG1056 in FlyBase
FLIGHTClick here to see CG1056 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG1056 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG1056
Entrez GeneEntrez Gene page for CG1056
UniprotUniprot page for CG1056

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)