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Gene Page - CG Number : CG10563
Gene Summary - CG10563:

CG10563: The gene lethal (2) 37Cd is referred to in FlyBase by the symbol Dmel\l(2)37Cd (CG10563, FBgn0086445). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: phagocytosis, engulfment. 17 alleles are reported. The phenotypes of these alleles are annotated with: macrochaeta; wing; melanotic mass. It has one annotated transcript and one annotated polypeptide. Protein features are: Transcription factor IIIC, subunit 5. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages.

Gene summary for CG10563 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10563:CG10563 is perturbed in following parameters in primary screen: Fint3
CG10563 is perturbed in following parameters in classification assay (fluid): LP_Fint1+ LP_Fint2+ LP_Fint3+ LP_Fint4- Okt+(fld) Rto1- Rto2- Rto3- SP_Fint4-
CG10563 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10563.
Cell Count:
CG_NumberCategoryR1R2R3
CG10563Primary screen59210235
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10563:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191251-0.636319426-0.905825626-0.4626666250.144969665-0.6560514550.8859629841.4066197340.9656640091.403975277-0.205887992-0.610488921-0.344559888-0.699294512-0.6194852310.973948971-0.291398665-1.033514847-0.628934919-0.9371615392.29976506-0.265550455-0.503916285-0.587775782
192350.1323599961.3489759693.420843218-1.578609578-3.038450589-1.7218351290.131536695-2.003881635-0.744958459-0.050646382-1.7811981171.660547432.3390110872.002728499-1.123141696-0.7964784132.1700769290.4295888082.918644704-1.563849637-0.018032665-3.533772606-4.303791552
1931856.5289484153.8364810913.618956512-0.148820327-0.2275274421.0914182814.9336635430.34542137-0.018766261-0.2143766680.485699901-0.5622731610.2561089040.28509785-0.741107204-0.522448332-0.389767381-0.615503959-0.433194311-0.205771786-0.804166358-0.8534010440.050565245
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10563Slide19C0.0001.3401.2821.311
CG10563Slide19O0.0491.7181.2931.349
CG10563Slide19P0.1691.0451.0601.132
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG10563 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
phagocytosis, engulfmentGO:0006911inferred from mutant phenotype
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
-
Other annotations
DatabaseLink
FlyBaseClick here to see CG10563 in FlyBase
FLIGHTClick here to see CG10563 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10563 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10563
Entrez GeneEntrez Gene page for CG10563
UniprotUniprot page for CG10563

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)