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Gene Page - CG Number : CG10579
Gene Summary - CG10579:

CG10579: The gene Ecdysone-induced protein 63E is referred to in FlyBase by the symbol Dmel\Eip63E (CG10579, FBgn0005640). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: cyclin-dependent protein kinase activity; cyclin binding; protein binding; protein kinase activity. There is experimental evidence that it is involved in the biological process: morphogenesis of an epithelium; instar larval development; developmental growth; embryonic development via the syncytial blastoderm; metamorphosis; protein phosphorylation. 53 alleles are reported. The phenotypes of these alleles are annotated with: pupa; leg; polytene chromosome; mesothoracic tergum. It has 14 annotated transcripts and 14 annotated polypeptides. Protein features are: Cytochrome b5, heme-binding site; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine- / dual-specificity protein kinase, catalytic domain; Serine/threonine-protein kinase, active site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period.

Gene summary for CG10579 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10579:CG10579 is not perturbed in primary screen.
CG10579 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10579.
Cell Count:
CG10579Primary screen632279283
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10579:
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10579 is not tested in classification assay
Integrated Annotations for CG10579 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
embryonic development via the syncytial blastodermGO:0001700inferred from mutant phenotype
instar larval development
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
cyclin-dependent protein kinase activityGO:0004693inferred from sequence or structural similarity
protein serine/threonine kinase activity
Other annotations
FlyBaseClick here to see CG10579 in FlyBase
FLIGHTClick here to see CG10579 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10579 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10579
Entrez GeneEntrez Gene page for CG10579
UniprotUniprot page for CG10579

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)