.:: RNAiDB - Gene Page ::. Gene Page - CG Number : CG1058Gene Summary - CG1058:CG1058: The gene ripped pocket is referred to in FlyBase by the symbol Dmel\rpk (CG1058, FBgn0022981). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ligand-gated sodium channel activity; sodium channel activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: sodium ion transport. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Na+ channel, amiloride-sensitive; Na+ channel, amiloride-sensitive, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. Gene summary for CG1058 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)Experimental Summary - CG1058:CG1058 is perturbed in following parameters in primary screen: Fmph1 Tint2 Tint3 Tmph1 CG1058 is perturbed in following parameters in classification assay (fluid): LP_Fint2+ LP_Fint3+ LP_Fmph1+ NuCirc+(fld) NuSize-(fld) SP_Fmph2- SP_Fmph3- SP_Fnum- CG1058 is not tested in classification assay (transferrin). Cellular phenotyping(Images): Click here to access phenotyping images of gene CG1058.Cell Count:CG_NumberCategoryR1R2R3CG1058Primary screen381208288R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3Primary screen data - CG1058: SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize SN: Slide Number; RN: Replicate Number; WN: Well NumberExperimental Data (Classification Assay):Fluid:CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3CG1058Slide19C0.0621.1391.1531.345CG1058Slide19O0.3491.6181.0361.046CG1058Slide19P0.1021.1001.0931.277C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex PulseIntegrated Annotations for CG1058 :Gene Ontology Annoations: Biological ProcessBiological Process - TermGO IDEvidencesodium ion transportGO:0006814inferred from electronic annotation with InterPro:IPR001873, InterPro:IPR020903Gene Ontology Annoations: Cellular ComponentCellular Component - TermGO IDEvidencemembraneGO:0016020inferred from electronic annotation with InterPro:IPR001873, InterPro:IPR020903Gene Ontology Annoations: Molecular FunctionMolecular Function - TermGO IDEvidencesodium channel activityGO:0005272inferred from sequence or structural similarity sodium channel activity Other annotations DatabaseLinkFlyBaseClick here to see CG1058 in FlyBaseFLIGHTClick here to see CG1058 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)BioGRIDClick here to see CG1058 in BioGRID (Interaction Summary)Off-targetClick here for Off-target data for CG1058Entrez GeneEntrez Gene page for CG1058UniprotUniprot page for CG1058 Endosite Team : Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in) Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)
.:: RNAiDB - Gene Page ::. Gene Page - CG Number : CG1058Gene Summary - CG1058:CG1058: The gene ripped pocket is referred to in FlyBase by the symbol Dmel\rpk (CG1058, FBgn0022981). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ligand-gated sodium channel activity; sodium channel activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: sodium ion transport. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Na+ channel, amiloride-sensitive; Na+ channel, amiloride-sensitive, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. Gene summary for CG1058 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)Experimental Summary - CG1058:CG1058 is perturbed in following parameters in primary screen: Fmph1 Tint2 Tint3 Tmph1 CG1058 is perturbed in following parameters in classification assay (fluid): LP_Fint2+ LP_Fint3+ LP_Fmph1+ NuCirc+(fld) NuSize-(fld) SP_Fmph2- SP_Fmph3- SP_Fnum- CG1058 is not tested in classification assay (transferrin). Cellular phenotyping(Images): Click here to access phenotyping images of gene CG1058.Cell Count:CG_NumberCategoryR1R2R3CG1058Primary screen381208288R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3Primary screen data - CG1058: SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize SN: Slide Number; RN: Replicate Number; WN: Well NumberExperimental Data (Classification Assay):Fluid:CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3CG1058Slide19C0.0621.1391.1531.345CG1058Slide19O0.3491.6181.0361.046CG1058Slide19P0.1021.1001.0931.277C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex PulseIntegrated Annotations for CG1058 :Gene Ontology Annoations: Biological ProcessBiological Process - TermGO IDEvidencesodium ion transportGO:0006814inferred from electronic annotation with InterPro:IPR001873, InterPro:IPR020903Gene Ontology Annoations: Cellular ComponentCellular Component - TermGO IDEvidencemembraneGO:0016020inferred from electronic annotation with InterPro:IPR001873, InterPro:IPR020903Gene Ontology Annoations: Molecular FunctionMolecular Function - TermGO IDEvidencesodium channel activityGO:0005272inferred from sequence or structural similarity sodium channel activity Other annotations DatabaseLinkFlyBaseClick here to see CG1058 in FlyBaseFLIGHTClick here to see CG1058 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)BioGRIDClick here to see CG1058 in BioGRID (Interaction Summary)Off-targetClick here for Off-target data for CG1058Entrez GeneEntrez Gene page for CG1058UniprotUniprot page for CG1058
CG1058: The gene ripped pocket is referred to in FlyBase by the symbol Dmel\rpk (CG1058, FBgn0022981). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ligand-gated sodium channel activity; sodium channel activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: sodium ion transport. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Na+ channel, amiloride-sensitive; Na+ channel, amiloride-sensitive, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
Endosite Team : Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in) Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)