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Gene Page - CG Number : CG10582
Gene Summary - CG10582:

CG10582: The gene Sex-lethal interactor is referred to in FlyBase by the symbol Dmel\Sin (CG10582, FBgn0028402). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. It is reported to be involved in the biological process: mRNA splicing, via spliceosome. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: DNA-directed RNA polymerase III subunit Rpc5. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during early larval stages, during early pupal stages, in adult female stages.

Gene summary for CG10582 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10582:CG10582 is not perturbed in primary screen.
CG10582 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10582.
Cell Count:
CG_NumberCategoryR1R2R3
CG10582Primary screen6792330
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10582:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191268-0.81500761-0.772030378-0.611475961-0.3466916360.3558934831.0381712080.6560092821.4059674650.8873532650.814473239-0.1526596041.4626977970.941068078-0.001029185-0.14019737-0.472868334-1.50565379-0.373975646-1.5273806651.471249890.306051832-0.206261195-0.298763679
19248-1.98676959-2.105283692-1.611882889-2.291974925-2.421671369-3.261324474-2.797294427-3.050902473-4.71215592-2.588772999-3.047716937-1.981889587-3.239588244-2.964384268-2.026406695-2.651606323-3.865114002-3.040624619-4.050080093-4.097396226-2.011903498-2.102983518-2.086670661
1931980.4831163620.5402765780.7707967650.2891256430.8287757270.8326832061.7778631630.6697111440.9475838640.8154784781.393410637-0.5624370370.8551896130.92301444-0.3602322220.6052845093.9276057441.2387505441.2919885751.25029427-0.5847738940.8168428452.327908
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10582 is not tested in classification assay
Integrated Annotations for CG10582 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
nuclear mRNA splicing, via spliceosomeGO:0000398inferred by curator from GO:0005685
transcription, DNA-dependent
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
U1 snRNPGO:0005685colocalizes_with non-traceable author statement
nucleus
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
protein bindingGO:0005515inferred from physical interaction with Sxl
DNA-directed RNA polymerase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10582 in FlyBase
FLIGHTClick here to see CG10582 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10582 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10582
Entrez GeneEntrez Gene page for CG10582
UniprotUniprot page for CG10582

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)