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Gene Page - CG Number : CG10583
Gene Summary - CG10583:

CG10583: The gene Separase is referred to in FlyBase by the symbol Dmel\Sse (CG10583, FBgn0035627). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: peptidase activity. There is experimental evidence that it is involved in the biological process: mitotic sister chromatid segregation; neurogenesis; phagocytosis, engulfment. 11 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mitotic cell cycle; cell cycle; mesothoracic tergum; imaginal disc. It has one annotated transcript and one annotated polypeptide. Protein features are: Peptidase C50, separase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages.

Gene summary for CG10583 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10583:CG10583 is not perturbed in primary screen.
CG10583 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10583.
Cell Count:
CG_NumberCategoryR1R2R3
CG10583Primary screen668339364
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10583:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191269-0.5760475961.3704909631.2351811940.3434676450.3884389961.008961141.6925385920.9570910031.7392713870.260794611.9076314182.504511017-0.000171275-0.135053735-0.3077110260.0201353040.8390083890.9688235531.7685424582.462571531-0.1499031523.9963315891.632735322
192470.5004786380.9987553380.311707262-0.4252071450.045971446-0.240278422-0.421012605-0.1841282210.4682313570.0939643040.2227664672.1219178830.946416150.097504736-0.0718627360.2933538180.6402118410.493991370.6056114390.476904423-0.4130213530.581083160.457391607
1931972.6226943854.4509882362.9943583331.5979338761.3222955252.8100750227.191628411.9618147542.282040591.1667154222.891585773-0.3622692120.2248161890.852220427-0.6787439111.8030753371.8953552841.6881568111.2788134062.9246382060.5740133660.9806325021.284026748
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10583 is not tested in classification assay
Integrated Annotations for CG10583 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
mitotic sister chromatid segregationGO:0000070inferred from mutant phenotype
meiosis I
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred from electronic annotation with InterPro:IPR005314
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
peptidase activityGO:0008233inferred from electronic annotation with InterPro:IPR005314
Other annotations
DatabaseLink
FlyBaseClick here to see CG10583 in FlyBase
FLIGHTClick here to see CG10583 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10583 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10583
Entrez GeneEntrez Gene page for CG10583
UniprotUniprot page for CG10583

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)