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Gene Page - CG Number : CG10588
Gene Summary - CG10588:

CG10588: This gene is referred to in FlyBase by the symbol Dmel\CG10588 (FBgn0037037). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: metalloendopeptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: proteolysis. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Metalloenzyme, LuxS/M16 peptidase-like, metal-binding; Peptidase M16, C-terminal; Peptidase M16, N-terminal; Peptidase M16, core; Peptidase M16, zinc-binding site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed in adult male stages.

Gene summary for CG10588 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10588:CG10588 is not perturbed in primary screen.
CG10588 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10588.
Cell Count:
CG_NumberCategoryR1R2R3
CG10588Primary screen845222123
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10588:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
1912740.0945182872.5835405283.6993509350.4323365480.5066596771.2123427942.4096807771.9071378272.482602433-0.514835916-0.4472940040.4012441241.1389513621.075042428-0.0379323880.814602091-1.8701485890.474175365-1.6186749862.6699788940.57253513210.894436395.494077766
19212-0.6213887810.358349510.8925182920.221681191-0.2388125341.006371271-0.2309285970.089742177-1.072319997-0.32422315-0.424117307-0.015152523-0.40507338-1.1733727620.471802791-0.840028497-0.781954256-0.549526632-1.52056635-0.700076432-0.228573481-0.789605914-0.860022602
193162-0.4618985142.2909345341.380344827-0.666525643-1.817866797-1.4563153710.260692285-1.997853241-2.075172982-1.197533002-0.8045476612.320763544-1.788817139-0.163885548-0.374923739-2.056395845-1.50769868-0.626103749-2.122797809-2.1765605680.2366768350.73792744-0.032668258
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10588 is not tested in classification assay
Integrated Annotations for CG10588 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
proteolysisGO:0006508inferred from electronic annotation with InterPro:IPR001431, InterPro:IPR007863, InterPro:IPR011765
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
metalloendopeptidase activityGO:0004222inferred from sequence or structural similarity with EMBL:X93208
zinc ion binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10588 in FlyBase
FLIGHTClick here to see CG10588 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10588 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10588
Entrez GeneEntrez Gene page for CG10588
UniprotUniprot page for CG10588

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)