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Gene Page - CG Number : CG10593
Gene Summary - CG10593:

CG10593: The gene Angiotensin-converting enzyme-related is referred to in FlyBase by the symbol Dmel\Acer (CG10593, FBgn0016122). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: peptidyl-dipeptidase activity. There is experimental evidence that it is involved in the biological process: heart development; positive regulation of circadian sleep/wake cycle, sleep; sleep. 7 alleles are reported. The phenotype of these alleles is annotated with: heart primordium. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Peptidase M2, peptidyl-dipeptidase A. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, during late pupal stages, in stages of adults of both sexes.

Gene summary for CG10593 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10593:CG10593 is not perturbed in primary screen.
CG10593 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10593.
Cell Count:
CG_NumberCategoryR1R2R3
CG10593Primary screen433223236
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10593:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191278-0.1705458020.0881586181.541690935-0.895492279-0.409032806-0.0170284420.5765460660.020492398-1.493852974-1.276835598-0.8513308530.709010686-1.1951267490.59678565-0.174793545-0.121697701-2.598515908-0.631263154-2.751459954-0.920987974-0.780064261-0.838045899-0.625591921
1928-0.8201641764.7704179682.2827147041.876832965-0.553830537-0.226071210.179204207-0.2092785720.2568976710.5090251030.6629691230.19173870.1201554590.037846575-0.549782207-0.5617608080.3433488861.6113472160.61135340.179312965-0.8414502531.4504264981.689815135
1931581.123244864-0.776679314-0.845832232-0.921745816-0.672998856-0.521522424-0.857929971-0.448027956-0.780254077-1.553366662-1.2532524282.879846522-0.904893054-1.0252765971.347225622-1.074818416-1.957290232-1.318094685-1.542203632-1.1557729560.1107128882.7064950514.09024606
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10593 is not tested in classification assay
Integrated Annotations for CG10593 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
heart developmentGO:0007507inferred from mutant phenotype
proteolysis
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
membraneGO:0016020inferred from electronic annotation with InterPro:IPR001548
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
peptidyl-dipeptidase activityGO:0008241inferred from sequence or structural similarity with Ance
peptidyl-dipeptidase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10593 in FlyBase
FLIGHTClick here to see CG10593 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10593 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10593
Entrez GeneEntrez Gene page for CG10593
UniprotUniprot page for CG10593

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)