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Gene Page - CG Number : CG10601
Gene Summary - CG10601:

CG10601: The gene mirror is referred to in FlyBase by the symbol Dmel\mirr (CG10601, FBgn0014343). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: sequence-specific DNA binding RNA polymerase II transcription factor activity; protein homodimerization activity. There is experimental evidence that it is involved in the biological process: smoothened signaling pathway; embryonic development via the syncytial blastoderm; equator specification; negative regulation of transcription from RNA polymerase II promoter; imaginal disc-derived wing morphogenesis; dorsal appendage formation; compound eye morphogenesis; peripheral nervous system development. 36 alleles are reported. The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: adult segment; organ system subdivision; organ system; acellular anatomical structure; thoracic segment; postalar bristle; imaginal precursor; eo support cell; cell part; larval head segment; external compound sense organ. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Homeobox KN domain; Homeobox, conserved site; Homeodomain; Homeodomain-like; Iroquois-class homeodomain protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-18 hour embryonic stages.

Gene summary for CG10601 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10601:CG10601 is not perturbed in primary screen.
CG10601 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10601.
Cell Count:
CG_NumberCategoryR1R2R3
CG10601Primary screen85811243
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10601:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191281-0.5804086880.1608476820.668310768-0.6570827111.4258920151.197628830.8990785481.7881407332.2565641690.1301174430.5669719860.0262900191.2749953571.0052092250.4648929990.2662238790.7181479521.5221290071.264441672.4704136781.3080128764.8664783384.298458117
19250.961998895-0.360451226-0.769439899-0.697582627-2.359621525-2.469100869-1.668049949-2.587952199-1.874760323-0.851978889-2.213983821-0.943632028-2.821088955-1.281907625-0.52321335-3.086139092-0.423271976-2.243947208-1.450434598-1.787488547-0.761133772-0.864024612-1.399527057
193155-0.245334484-0.4853044530.148612343-0.622427453-0.601380486-1.188795567-1.568145236-0.95122557-0.2884915620.494569251.0008072960.541112874-0.232326270.1250174110.542709772-0.2132592530.3570039740.4467729560.009078467-0.2467169260.235136624-0.3298119470.447304404
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10601 is not tested in classification assay
Integrated Annotations for CG10601 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
embryonic development via the syncytial blastodermGO:0001700inferred from expression pattern AND inferred from mutant phenotype
equator specification
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred from sequence or structural similarity with InterPro:IPR001356
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
sequence-specific DNA binding transcription factor activityGO:0003700inferred from sequence or structural similarity with InterPro:IPR001356
sequence-specific DNA binding transcription factor activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10601 in FlyBase
FLIGHTClick here to see CG10601 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10601 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10601
Entrez GeneEntrez Gene page for CG10601
UniprotUniprot page for CG10601

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)