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Gene Page - CG Number : CG10605
Gene Summary - CG10605:

CG10605: The gene caupolican is referred to in FlyBase by the symbol Dmel\caup (CG10605, FBgn0015919). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity. There is experimental evidence that it is involved in the biological process: imaginal disc-derived wing vein specification; compound eye morphogenesis; muscle cell fate commitment; phagocytosis, engulfment. 15 alleles are reported. The phenotypes of these alleles are annotated with: mesothoracic segment; eye; macrochaeta; notopleural suture; vertical bristle; wing; microchaeta; ommatidium; scutellum. It has one annotated transcript and one annotated polypeptide. Protein features are: Homeobox KN domain; Homeobox, conserved site; Homeodomain; Homeodomain-like; Iroquois-class homeodomain protein. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 06-18 hour embryonic stages.

Gene summary for CG10605 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10605:CG10605 is not perturbed in primary screen.
CG10605 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10605.
Cell Count:
CG_NumberCategoryR1R2R3
CG10605Primary screen528118399
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10605:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191285-0.5283084271.5507653372.6950609920.0405534610.3169055680.4877761921.4846712580.6951007510.00929699-1.212303811-1.097135697-0.4965907-0.781890576-0.1055194350.8162399990.03517798-0.983021035-1.152677729-1.0067755210.1461271180.6731212672.503185115-0.265694162
19212.4111896742.690264836-0.3883065330.478884662-1.144063222-0.4534691031.606660625-0.1189047310.3903143921.1239235180.9027374730.7285160681.0380501352.0681754970.062293765-0.0763557752.1404059021.966087022.7391060050.361633107-0.4580679040.658684716-0.086736776
1931510.7101925781.8921631680.643486569-0.4427294720.8113746291.0480693812.8209969231.1374616991.5242116291.3909471172.8588957880.0129108762.466382771.642373877-0.3452699711.0933451281.5397023541.3026952611.4048312421.5785990750.649406735-0.662021102-0.3981952
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10605 is not tested in classification assay
Integrated Annotations for CG10605 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
equator specificationGO:0045317traceable author statement
regulation of transcription from RNA polymerase II promoter
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634non-traceable author statement
nucleus
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
sequence-specific distal enhancer binding RNA polymerase II transcription factor activityGO:0003705inferred from sequence or structural similarity with ara
sequence-specific DNA binding transcription factor activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10605 in FlyBase
FLIGHTClick here to see CG10605 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10605 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10605
Entrez GeneEntrez Gene page for CG10605
UniprotUniprot page for CG10605

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)