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Gene Page - CG Number : CG10610
Gene Summary - CG10610:

CG10610: The gene ECSIT is referred to in FlyBase by the symbol Dmel\ECSIT (CG10610, FBgn0028436). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding. There is experimental evidence that it is involved in the biological process: innate immune response. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: ECSIT. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed during early larval stages.

Gene summary for CG10610 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10610:CG10610 is not perturbed in primary screen.
CG10610 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10610.
Cell Count:
CG_NumberCategoryR1R2R3
CG10610Primary screen794225312
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10610:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191286-0.5974585521.8413993482.309989666-0.0868051681.177918293-0.076101506-0.819320045-0.0641392282.7636656590.4778013463.3330208951.2254605760.9922068331.12843601-0.145029045-0.2560007591.8716152974.4145919952.1910507812.507008239-0.29519432210.44264086.685635551
192300.184705457-0.7473707310.721022465-0.830179749-0.427983161-0.0844638772.034849611-0.310745810.328119174-0.236672564-0.4920204121.2855990760.3605900381.1555915521.021921588-0.8309929350.190241320.63575927-0.6066767220.566795850.018735768-0.077621379-0.634797923
1931803.5854400542.4501939370.037823835-0.158036750.1386141570.2589237111.0388164030.4538219951.337873471-0.557042938-0.292687645-0.6245212910.395376091-0.4282981490.1634720543.4290530241.3046011361.9148864451.9869224222.0348789412.539929749-0.3197815610.190194173
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10610 is not tested in classification assay
Integrated Annotations for CG10610 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
innate immune responseGO:0045087inferred from direct assay
Toll signaling pathway
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
protein bindingGO:0005515inferred from physical interaction with Traf6
Other annotations
DatabaseLink
FlyBaseClick here to see CG10610 in FlyBase
FLIGHTClick here to see CG10610 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10610 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10610
Entrez GeneEntrez Gene page for CG10610
UniprotUniprot page for CG10610

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)