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Gene Page - CG Number : CG10619
Gene Summary - CG10619:

CG10619: The gene tailup is referred to in FlyBase by the symbol Dmel\tup (CG10619, FBgn0003896). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: RNA polymerase II regulatory region sequence-specific DNA binding; protein binding; RNA polymerase II distal enhancer sequence-specific DNA binding; RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity; RNA polymerase II activating transcription factor binding. There is experimental evidence for 16 unique biological process terms, many of which group under: system development; biological regulation; cellular component organization or biogenesis; embryonic development via the syncytial blastoderm; embryo development ending in birth or egg hatching; neuron differentiation; sensory organ development; cell fate commitment; regulation of RNA metabolic process; neuron projection development. 22 alleles are reported. The phenotypes of these alleles are annotated with 43 unique terms, many of which group under: organ system subdivision; adult segment; organ system; adult antennal lobe; adult uniglomerular antennal lobe projection neuron adPN; cephalopharyngeal skeleton; projection neuron; hypodermal muscle of larval abdomen; appendage segment; thoracic segment. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Homeobox, conserved site; Homeodomain; Homeodomain-like; Zinc finger, LIM-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-18 hour embryonic stages.

Gene summary for CG10619 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10619:CG10619 is not perturbed in primary screen.
CG10619 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10619.
Cell Count:
CG_NumberCategoryR1R2R3
CG10619Primary screen834347397
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10619:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191290-0.419649665-0.3147433860.217334313-0.3653347930.7024611791.3098911360.9612097571.5300066092.148678123-0.5782895971.6787105940.6752536820.5315007180.080469712-0.623670010.3059978741.1988011581.0375713862.6138509122.368215247-0.0742997074.2058965452.864695789
192260.9097783230.088539373-0.2255396511.118519166-0.0956976140.0306168630.656397540.1960718260.408888163-0.1903044390.2167341441.1811771990.8174054551.763608205-0.1179588650.0944971810.1740471230.504208485-0.2390422430.603670635-0.598482320.1333141350.313064444
193176-0.539659006-0.121865173-0.323034657-0.2782463290.9447837861.3011777823.0034439151.2777179991.6447367340.020630644-0.2594254120.0893779681.3685586180.889127139-0.4556265210.3994622630.3898269340.3163287660.5967281271.941499953-0.001589001-0.157963637-0.435323639
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10619 is not tested in classification assay
Integrated Annotations for CG10619 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
terminal region determinationGO:0007362inferred from genetic interaction with tor
torso signaling pathway
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred from direct assay
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
RNA polymerase II distal enhancer sequence-specific DNA bindingGO:0000980inferred from direct assay
sequence-specific distal enhancer binding RNA polymerase II transcription factor activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10619 in FlyBase
FLIGHTClick here to see CG10619 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10619 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10619
Entrez GeneEntrez Gene page for CG10619
UniprotUniprot page for CG10619

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)