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Gene Page - CG Number : CG10622
Gene Summary - CG10622:

CG10622: The gene Sucb is referred to in FlyBase by the symbol Dmel\Sucb (CG10622, FBgn0029118). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: succinate-CoA ligase (GDP-forming) activity. Based on sequence similarity, it is predicted to be involved in the biological process: tricarboxylic acid cycle. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: ATP-citrate lyase/succinyl-CoA ligase; ATP-grasp fold, subdomain 1; ATP-grasp fold, subdomain 2; ATP-grasp fold, succinyl-CoA synthetase-type; Succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase, beta subunit, conserved site; Succinyl-CoA synthetase-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 06-12 hour embryonic stages, at stages throughout the larval period.

Gene summary for CG10622 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10622:CG10622 is not perturbed in primary screen.
CG10622 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10622.
Cell Count:
CG_NumberCategoryR1R2R3
CG10622Primary screen561525319
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10622:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191292-0.3663738443.1801859242.62304985-0.8131713360.2031384930.334067634-0.0309317670.3843340932.2683885022.7613505913.419583891-0.6427800740.9935635241.086087820.926616027-0.2888888283.065294846.9946129874.9035559633.1184537690.5718190671.5566021050.107627172
19224-0.861928103-0.515416854-0.466588299-0.079130950.5721010560.9000114161.4385888870.8691994270.8425596030.7622861120.776741060.1555467711.881837692.6944582781.0263431170.5011793280.9990567880.0317763410.3148918150.897484071-0.52860047-0.507316171-0.073563393
193174-0.0939944460.2006038060.087584395-0.297926708-0.030978213-0.023739553-0.2321268540.105161817-0.746612333-0.785512856-0.4641448410.503158366-0.21460491-1.051970225-0.391365291-0.378222241-0.289091525-0.46067129-0.288454927-0.825975525-0.7133231620.268030389-0.767197912
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10622 is not tested in classification assay
Integrated Annotations for CG10622 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
tricarboxylic acid cycleGO:0006099inferred from sequence or structural similarity with UniProtKB:Q96I99
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
lipid particleGO:0005811inferred from direct assay
succinate-CoA ligase complex (GDP-forming)
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
succinate-CoA ligase (GDP-forming) activityGO:0004776non-traceable author statement
succinate-CoA ligase (GDP-forming) activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10622 in FlyBase
FLIGHTClick here to see CG10622 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10622 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10622
Entrez GeneEntrez Gene page for CG10622
UniprotUniprot page for CG10622

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)