Home Browse SearchHelp DownloadGroup

.:: RNAiDB - Gene Page ::.
Gene Page - CG Number : CG10626
Gene Summary - CG10626:

CG10626: The gene Leucokinin receptor is referred to in FlyBase by the symbol Dmel\Lkr (CG10626, FBgn0035610). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: leucokinin receptor activity. Based on sequence similarity, it is predicted to be involved in the biological process: G-protein coupled receptor signaling pathway; tachykinin receptor signaling pathway. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: GPCR, rhodopsin-like; GPCR, rhodopsin-like, 7TM; Neuropeptide Y receptor. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of no expression detected. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages.

Gene summary for CG10626 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10626:CG10626 is perturbed in following parameters in primary screen: Fint2
CG10626 is perturbed in following parameters in classification assay (fluid): CellSize-(fld) LP_Fint3+ LP_Fint4- Rto3+ SP_Fint3+ SP_Fint4- SP_Fmph2- SP_Fnum-
CG10626 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10626.
Cell Count:
CG_NumberCategoryR1R2R3
CG10626Primary screen700355415
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10626:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
1912940.3523348713.1186695942.3695668940.6612116170.6392117970.8941502021.9357135011.3067386811.707875883-0.550512039-0.5868997091.5679321743.5391651692.139078208-0.04910978-0.378182011-2.189303264-0.476839492-2.1910417991.975540371-0.3993177940.5132383561.214807796
19222-0.206988224-0.472529919-0.17005742-0.3694657210.0310396620.1932064131.541642519-0.007956540.044486032-0.220028741-0.166260494-0.270960033-0.247923760.081389118-0.4709610580.2174306640.373537459-0.244093135-0.170253280.761097945-0.66334205-0.428654071-0.267279164
1931722.7401269153.6454584532.2362192890.2812551681.8683351353.1608302677.2048965072.084889722.08048551.1077834611.0057837240.260017032.2949289021.678427370.5424057170.5083330051.2068071340.8217183751.154136322.782706184-0.0560218550.2554142250.213121065
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10626Slide19C0.0601.0561.0871.164
CG10626Slide19O0.8171.1571.0420.895
CG10626Slide19P0.0421.1761.0821.217
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG10626 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
tachykinin receptor signaling pathwayGO:0007217inferred from sequence or structural similarity with Takr99D
G-protein coupled receptor signaling pathway
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
integral to membraneGO:0016021inferred from sequence or structural similarity with Takr99D
integral to membrane
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
tachykinin receptor activityGO:0004995inferred from sequence or structural similarity with Takr99D
neuropeptide receptor activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10626 in FlyBase
FLIGHTClick here to see CG10626 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10626 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10626
Entrez GeneEntrez Gene page for CG10626
UniprotUniprot page for CG10626

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)