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Gene Page - CG Number : CG10627
Gene Summary - CG10627:

CG10627: The gene nesthocker is referred to in FlyBase by the symbol Dmel\nst (CG10627, FBgn0036298). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: phosphoacetylglucosamine mutase activity. There is experimental evidence that it is involved in the biological process: trachea development; UDP-N-acetylglucosamine biosynthetic process; mesoderm formation; positive regulation of fibroblast growth factor receptor signaling pathway. 9 alleles are reported. The phenotype of these alleles is annotated with: mesoderm. It has one annotated transcript and one annotated polypeptide. Protein features are: Alpha-D-phosphohexomutase, C-terminal; Alpha-D-phosphohexomutase, alpha/beta/alpha I/II/III; Alpha-D-phosphohexomutase, alpha/beta/alpha domain I; Alpha-D-phosphohexomutase, alpha/beta/alpha domain II; Alpha-D-phosphohexomutase, alpha/beta/alpha domain III; Alpha-D-phosphohexomutase, conserved site; Phosphoacetylglucosamine mutase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 12-18 embryonic stages.

Gene summary for CG10627 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10627:CG10627 is not perturbed in primary screen.
CG10627 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10627.
Cell Count:
CG_NumberCategoryR1R2R3
CG10627Primary screen604433504
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10627:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
191295-0.747852043-0.1633737020.148153924-0.2166490220.2826586050.8636549620.2642755270.6647759690.820843345-0.3173196080.337071261.3634269650.064609168-0.359499423-0.282168287-0.032300419-0.803113560.196773333-0.624794170.552101032-0.0091455041.2051320512.669856082
192210.3256726711.3646624270.1558462390.3786708530.4654450731.0135601143.3299714480.8892887651.318025514-0.3632259840.2385824270.0470676031.1232695710.439203520.2596158260.0686756350.6562774260.9187035770.0662105691.8371662920.1370160361.664705612.218204564
193171-0.361385735-0.0425770980.2253840830.2426358231.5436453661.5335244661.7808395621.6715896821.4305686420.3045449851.196340314-0.4065690481.5898301050.7251742460.8179185371.8428175520.8746615330.3618052451.0423932361.37104441-0.0632430060.1585719221.499458369
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10627 is not tested in classification assay
Integrated Annotations for CG10627 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
mesoderm formationGO:0001707inferred from mutant phenotype
trachea development
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
phosphoacetylglucosamine mutase activityGO:0004610inferred from sequence or structural similarity with UniProtKB:P38628
magnesium ion binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10627 in FlyBase
FLIGHTClick here to see CG10627 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10627 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10627
Entrez GeneEntrez Gene page for CG10627
UniprotUniprot page for CG10627

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)