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Gene Page - CG Number : CG1064
Gene Summary - CG1064:

CG1064: The gene Snf5-related 1 is referred to in FlyBase by the symbol Dmel\Snr1 (CG1064, FBgn0011715). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: SET domain binding; protein binding. There is experimental evidence that it is involved in the biological process: imaginal disc-derived wing margin morphogenesis; dendrite morphogenesis; imaginal disc-derived wing vein morphogenesis; imaginal disc-derived wing vein specification; muscle organ development; positive regulation of transcription, DNA-dependent; epidermis development; negative regulation of cell proliferation; dendrite guidance. 23 alleles are reported. The phenotypes of these alleles are annotated with: wing margin; adult antennal lobe projection neuron DL1 adPN; wing; tergite; wing vein; wing vein L2. It has one annotated transcript and one annotated polypeptide. Protein features are: SNF5/SMARCB1/INI1; SWI/SNF chromatin-remodeling complex, component hSNF5/Ini1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages.

Gene summary for CG1064 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG1064:CG1064 is perturbed in following parameters in primary screen: Rto2 Tmph1
CG1064 is not tested in classification assay (fluid).
CG1064 is perturbed in following parameters in classification assay (transferrin): CellSize-(tfr) Fclc- Fint1- Fint2- Fint3- Fmph1- Fmph2- Fmph3- Fnum- Tclc- Tmph1- Tnum-
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG1064.
Cell Count:
CG_NumberCategoryR1R2R3
CG1064Primary screen2629128
CG1064Secondary assay64312401455
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG1064:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Transferrin:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG1064Slide1F0.0840.8750.8770.914
CG1064Slide1O0.6980.9230.9791.035
CG1064Slide1T0.0280.7740.5500.456
F=Fdex; O=Surface TfR (Okt9); T=Tf

Integrated Annotations for CG1064 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
positive regulation of transcription, DNA-dependentGO:0045893inferred from direct assay
embryonic development via the syncytial blastoderm
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634non-traceable author statement
brahma complex
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
transcription coactivator activityGO:0003713contributes_to inferred by curator from GO:0035060
SET domain binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG1064 in FlyBase
FLIGHTClick here to see CG1064 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG1064 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG1064
Entrez GeneEntrez Gene page for CG1064
UniprotUniprot page for CG1064

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)