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Gene Page - CG Number : CG10672
Gene Summary - CG10672:

CG10672: This gene is referred to in FlyBase by the symbol Dmel\CG10672 (FBgn0035588). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: oxidoreductase activity, acting on CH-OH group of donors. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: metabolic process. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Glucose/ribitol dehydrogenase; NAD(P)-binding domain; Short-chain dehydrogenase/reductase SDR; Short-chain dehydrogenase/reductase, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed during early larval stages.

Gene summary for CG10672 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10672:CG10672 is perturbed in following parameters in primary screen: Fmph2 Tclc
CG10672 is perturbed in following parameters in classification assay (fluid): CellSize-(fld) LP_Fint2+ LP_Fint4- LP_Fmph2- LP_Fnum- SP_Fint4-
CG10672 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10672.
Cell Count:
CG_NumberCategoryR1R2R3
CG10672Primary screen740254542
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10672:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
20120-0.6065246935.2815848494.3946782291.3058271210.4648793971.1178783181.7700121461.2220893112.559189189-0.0446196680.0777728511.2703505930.846780580.170063096-0.090334847-0.5304787472.3734893443.0588774872.7764633773.127057893-0.2674377286.6495353334.884279687
2021761.917489782.030115660.7495750590.0231389320.6022335863.8217770754.3396969743.7807730560.953295505-0.357934994-0.2690957910.1464244661.7842238790.902255855-1.041347721-0.601814614-0.1441676420.1702900530.2726487371.554855978-0.162043089-0.5312109040.049416797
2031462.45829770.1277910631.446526703-0.4006289791.6924444522.8496311766.1438797542.1149305752.959304137-0.953879647-0.4071367210.2535005192.4074103861.956217789-0.0682752451.4638952441.4724534711.3054928641.6973460773.079420765-0.123617181.5047207131.539425992
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10672Slide19C0.1391.1981.6381.181
CG10672Slide19O0.1841.0281.6121.328
CG10672Slide19P0.3421.0981.2460.972
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG10672 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
metabolic processGO:0008152inferred from electronic annotation with InterPro:IPR002198
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
oxidoreductase activity, acting on CH-OH group of donorsGO:0016614inferred from sequence or structural similarity with EMBL:AF044127
nucleotide binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10672 in FlyBase
FLIGHTClick here to see CG10672 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10672 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10672
Entrez GeneEntrez Gene page for CG10672
UniprotUniprot page for CG10672

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)