Gene Page - CG Number : CG10682

Gene Summary - CG10682:

CG10682: The gene vihar is referred to in FlyBase by the symbol Dmel\vih (CG10682, FBgn0264848). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: ubiquitin-protein ligase activity. There is experimental evidence that it is involved in the biological process: regulation of cell cycle. 15 alleles are reported. The phenotype of these alleles is annotated with: spindle. It has one annotated transcript and one annotated polypeptide. Protein features are: Ubiquitin-conjugating enzyme, E2; Ubiquitin-conjugating enzyme, active site; Ubiquitin-conjugating enzyme/RWD-like. Gene sequence location is 3L:12497392..12498921.

Gene summary for CG10682 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)

Experimental Summary - CG10682:

CG10682 is perturbed in following parameters in primary screen: Fmph2
CG10682 is perturbed in following parameters in classification assay (fluid): CellSize+(fld) LP_Fclc- NuCellD+(fld) Okt+(fld) Rto3- SP_Fclc-
CG10682 is not tested in classification assay (transferrin).

Cellular phenotyping(Images):

Click here to access phenotyping images of gene CG10682.

Cell Count:

CG_Number	Category	R1	R2	R3
CG10682	Primary screen	603	385	310

R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3

Primary screen data - CG10682:

SN	RN	WN	Fint1	Fint2	Fint3	Fint4	Fnum	Fmph1	Fmph2	Fmph3	Fclc	Tint1	Tint2	Tint3	Tint4	Rto1	Rto2	Rto3	Okt	Tnum	Tmph1	Tmph2	Tmph3	Tclc	CellSize
20	1	24	1.426915534	1.6515108	1.920406537	1.958947557	0.256073408	2.111262637	3.074418233	1.083956922	1.713448093	-0.902754466	-0.67430019	-0.496709415	0.634070903	1.489768503	0.214400662	-0.325669407	-1.080493012	-1.002133529	-1.979309794	3.539295171	-0.518739145	5.575005022	3.406055873
20	2	172	0.824154044	-0.0534356	-0.232929474	-0.62418941	0.223454928	-0.6653992	-0.842779307	-1.056855831	0.019302963	-0.400142866	-0.090090643	-0.181843899	0.126101068	0.256707977	-0.108885434	-0.343962727	-0.380587094	0.050929634	-0.61262668	0.080620472	-0.561522323	-0.370717063	0.36427765
20	3	142	0.07923118	1.22776181	1.158887086	0.251058742	0.463941932	2.293596591	4.830543677	1.350437739	1.717402555	1.697961661	3.070866854	3.068653309	3.653939756	2.82648897	-0.117061505	1.647968952	1.418524213	2.117598409	1.540168204	2.403143124	0.899863765	0.995520382	0.961066838

SN: Slide Number; RN: Replicate Number; WN: Well Number

Experimental Data (Classification Assay):

Fluid:

CG_Number	Slide No.	ttest P-value	Ratio 1	Ratio 2	Ratio 3
CG10682	Slide19C	0.393	0.889	1.420	1.190
CG10682	Slide19O	0.035	1.092	1.184	1.175
CG10682	Slide19P	0.361	0.876	1.055	0.818

C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG10682 :

Gene Ontology Annoations: Biological Process

Biological Process - Term	GO ID	Evidence
regulation of cell cycle	GO:0051726	inferred from mutant phenotype

Gene Ontology Annoations: Cellular Component

Cellular Component - Term	GO ID	Evidence
-

Gene Ontology Annoations: Molecular Function

Molecular Function - Term	GO ID	Evidence
ubiquitin-protein ligase activity	GO:0004842	inferred from direct assay ubiquitin-protein ligase activity

Other annotations

Database	Link
FlyBase	Click here to see CG10682 in FlyBase
FLIGHT	Click here to see CG10682 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRID	Click here to see CG10682 in BioGRID (Interaction Summary)
Off-target	Click here for Off-target data for CG10682
Entrez Gene	Entrez Gene page for CG10682
Uniprot	Uniprot page for CG10682

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Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)