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Gene Page - CG Number : CG10682
Gene Summary - CG10682:

CG10682: The gene vihar is referred to in FlyBase by the symbol Dmel\vih (CG10682, FBgn0264848). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: ubiquitin-protein ligase activity. There is experimental evidence that it is involved in the biological process: regulation of cell cycle. 15 alleles are reported. The phenotype of these alleles is annotated with: spindle. It has one annotated transcript and one annotated polypeptide. Protein features are: Ubiquitin-conjugating enzyme, E2; Ubiquitin-conjugating enzyme, active site; Ubiquitin-conjugating enzyme/RWD-like. Gene sequence location is 3L:12497392..12498921.

Gene summary for CG10682 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10682:CG10682 is perturbed in following parameters in primary screen: Fmph2
CG10682 is perturbed in following parameters in classification assay (fluid): CellSize+(fld) LP_Fclc- NuCellD+(fld) Okt+(fld) Rto3- SP_Fclc-
CG10682 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10682.
Cell Count:
CG_NumberCategoryR1R2R3
CG10682Primary screen603385310
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10682:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201241.4269155341.65151081.9204065371.9589475570.2560734082.1112626373.0744182331.0839569221.713448093-0.902754466-0.67430019-0.4967094150.6340709031.4897685030.214400662-0.325669407-1.080493012-1.002133529-1.9793097943.539295171-0.5187391455.5750050223.406055873
2021720.824154044-0.0534356-0.232929474-0.624189410.223454928-0.6653992-0.842779307-1.0568558310.019302963-0.400142866-0.090090643-0.1818438990.1261010680.256707977-0.108885434-0.343962727-0.3805870940.050929634-0.612626680.080620472-0.561522323-0.3707170630.36427765
2031420.079231181.227761811.1588870860.2510587420.4639419322.2935965914.8305436771.3504377391.7174025551.6979616613.0708668543.0686533093.6539397562.82648897-0.1170615051.6479689521.4185242132.1175984091.5401682042.4031431240.8998637650.9955203820.961066838
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10682Slide19C0.3930.8891.4201.190
CG10682Slide19O0.0351.0921.1841.175
CG10682Slide19P0.3610.8761.0550.818
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG10682 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
regulation of cell cycleGO:0051726inferred from mutant phenotype
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
ubiquitin-protein ligase activityGO:0004842inferred from direct assay
ubiquitin-protein ligase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10682 in FlyBase
FLIGHTClick here to see CG10682 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10682 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10682
Entrez GeneEntrez Gene page for CG10682
UniprotUniprot page for CG10682

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)