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Gene Page - CG Number : CG10687
Gene Summary - CG10687:

CG10687: The gene Asparaginyl-tRNA synthetase is referred to in FlyBase by the symbol Dmel\Aats-asn (CG10687, FBgn0086443). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: asparagine-tRNA ligase activity. It is reported to be involved in the biological process: asparaginyl-tRNA aminoacylation. 53 alleles are reported. The phenotypes of these alleles are annotated with: adult thorax; adult head; metathoracic bristle; scutellar bristle; wing; mesothoracic bristle. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Aminoacyl-tRNA synthetase, class II; Aminoacyl-tRNA synthetase, class II (D/K/N); Aminoacyl-tRNA synthetase, class II (D/K/N)-like; Asparagine-tRNA ligase, class IIb; Aspartyl/Asparaginyl-tRNA synthetase, class IIb; Nucleic acid binding, OB-fold, tRNA/helicase-type; Nucleic acid-binding, OB-fold; Nucleic acid-binding, OB-fold-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in adult female stages.

Gene summary for CG10687 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10687:CG10687 is not perturbed in primary screen.
CG10687 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10687.
Cell Count:
CG_NumberCategoryR1R2R3
CG10687Primary screen609312402
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10687:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
20125-0.38494420.6992747471.845270502-0.629782792-0.312771830.717317451.7938795061.1519471921.1891541380.731696391-0.2610319510.915025888-0.891867799-0.458407874-0.6367241740.263367235-0.662257376-0.218362355-1.0739623032.2555471250.9224607333.6096055382.389022187
202171-0.6456831740.38300442-0.676933383-0.350070036-0.223499814-1.113684551-0.902998752-0.743813391-0.0843575510.0603483620.104751228-0.0599193120.3214725390.3559447980.135535626-0.0002035640.276647670.0239076360.2832251940.0849315710.396095967-0.3322331970.322098122
2031410.0145275840.229423525-0.381236589-0.4365714620.7434552491.0730709290.9220785731.1001990271.1152883371.0029389062.071045447-0.3326071412.0362921411.1295874331.4047922170.7794610551.075916230.7952754651.3581776661.084425792-0.657468795-0.0882961720.785203891
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10687 is not tested in classification assay
Integrated Annotations for CG10687 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
asparaginyl-tRNA aminoacylationGO:0006421non-traceable author statement
asparaginyl-tRNA aminoacylation
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cytoplasmGO:0005737inferred from electronic annotation with InterPro:IPR002312, InterPro:IPR004364, InterPro:IPR004522, InterPro:IPR006195, InterPro:IPR018150
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
asparagine-tRNA ligase activityGO:0004816inferred from sequence or structural similarity with EMBL:D84273; protein_id:AJ000334.1 AND non-traceable author statement
ATP binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10687 in FlyBase
FLIGHTClick here to see CG10687 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10687 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10687
Entrez GeneEntrez Gene page for CG10687
UniprotUniprot page for CG10687

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)