Gene Page - CG Number : CG10691

Gene Summary - CG10691:

CG10691: The gene lethal (2) 37Cc is referred to in FlyBase by the symbol Dmel\l(2)37Cc (CG10691, FBgn0002031). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: cellular response to hypoxia. 43 alleles are reported. The phenotypes of these alleles are annotated with: yolk; cystocyte; trichogen cell; egg; macrochaeta; mesothoracic tergum; wing; egg chamber. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Band 7 protein; Prohibitin. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in adult female stages.

Gene summary for CG10691 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)

Experimental Summary - CG10691:

CG10691 is not perturbed in primary screen.
CG10691 is not tested in classification assay.

Cellular phenotyping(Images):

Click here to access phenotyping images of gene CG10691.

Cell Count:

CG_Number	Category	R1	R2	R3
CG10691	Primary screen	865	409	362

R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3

Primary screen data - CG10691:

SN	RN	WN	Fint1	Fint2	Fint3	Fint4	Fnum	Fmph1	Fmph2	Fmph3	Fclc	Tint1	Tint2	Tint3	Tint4	Rto1	Rto2	Rto3	Okt	Tnum	Tmph1	Tmph2	Tmph3	Tclc	CellSize
20	1	28	-0.536475182	0.976041826	1.26241888	1.020844273	1.463543871	1.078866126	0.559595439	1.061027041	2.19089728	-0.278913843	0.925217666	-0.870980431	-0.290673895	0.634746233	0.713646188	0.595604749	1.022670564	0.47259255	1.900780819	3.074646099	-0.120825685	5.002822177	4.034750756
20	2	168	-0.847218493	-0.209396628	-0.597247249	-0.94692673	0.359935583	-0.605234402	-0.419974722	-0.304754805	0.103363626	-0.332181643	-0.191929148	-0.278170855	-0.335725868	-0.033793753	-0.27107324	0.510164332	0.103647331	0.764146763	-0.024402997	0.301692539	-0.339641342	-0.299654666	-0.713878386
20	3	138	1.545921407	1.961985347	2.581747353	-0.307670196	0.693340497	1.231467884	2.794114151	1.023465021	0.742119808	1.192194536	0.2745611	0.757754335	0.163207883	-0.140602084	0.459469918	0.058022336	0.094968449	-0.065175885	-0.285231226	0.707018649	0.659242796	-0.162780206	-0.375665593

SN: Slide Number; RN: Replicate Number; WN: Well Number

Experimental Data (Classification Assay):

CG10691 is not tested in classification assay

Integrated Annotations for CG10691 :

Gene Ontology Annoations: Biological Process

Biological Process - Term	GO ID	Evidence
instar larval or pupal development	GO:0002165	non-traceable author statement cellular response to hypoxia

Gene Ontology Annoations: Cellular Component

Cellular Component - Term	GO ID	Evidence
lipid particle	GO:0005811	inferred from direct assay cytoplasm

Gene Ontology Annoations: Molecular Function

Molecular Function - Term	GO ID	Evidence
-

Other annotations

Database	Link
FlyBase	Click here to see CG10691 in FlyBase
FLIGHT	Click here to see CG10691 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRID	Click here to see CG10691 in BioGRID (Interaction Summary)
Off-target	Click here for Off-target data for CG10691
Entrez Gene	Entrez Gene page for CG10691
Uniprot	Uniprot page for CG10691

---

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)