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Gene Page - CG Number : CG10693
Gene Summary - CG10693:

CG10693: The gene slowpoke is referred to in FlyBase by the symbol Dmel\slo (CG10693, FBgn0003429). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; calcium-activated potassium channel activity. There is experimental evidence that it is involved in the biological process: male courtship behavior, veined wing generated song production; circadian rhythm; potassium ion transport; circadian behavior; response to drug. 45 alleles are reported. The phenotypes of these alleles are annotated with: neuron; neuromuscular junction; indirect flight muscle. It has 23 annotated transcripts and 23 annotated polypeptides. Protein features are: Calcium-activated potassium channel Slo; Ion transport 2; Ion transport domain; NAD(P)-binding domain; Potassium channel, calcium-activated, BK, alpha subunit; Voltage-dependent potassium channel. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.

Gene summary for CG10693 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10693:CG10693 is not perturbed in primary screen.
CG10693 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10693.
Cell Count:
CG_NumberCategoryR1R2R3
CG10693Primary screen213362259
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10693:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201302.2956981665.93852740515.8165197.2558139451.7164153559.5768849247.28386750610.6476944812.850845720.733284935.1999777952.6721328278.5484926026.47386840517.036657284.37841270224.5573870317.0385880640.361990989.6928786240.742436561.8543124560.288998667
2021660.921470563-0.43575428-0.249071759-0.402480309-0.05155907-0.026488210.17672055-0.0158823560.3349639880.4523493150.487390235-0.4509707562.834203211.769675766-0.3976493910.0230980751.3387889130.49430410.9211702410.248014325-0.634221249-0.541082936-0.629980509
2031362.2875853951.6083960451.135573013-0.8930850170.482905370.4233206771.3051805050.1776834820.10005705-0.7776900360.5852627180.748190987-0.351812404-0.270615053-0.187231257-0.749517299-0.432990999-0.055048863-1.35978322-0.088466994-0.47791286-0.804779083-0.53668298
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10693 is not tested in classification assay
Integrated Annotations for CG10693 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
potassium ion transportGO:0006813inferred from direct assay
circadian rhythm
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
plasma membraneGO:0005886non-traceable author statement
neuron projection
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
calcium-activated potassium channel activityGO:0015269inferred from direct assay
protein binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10693 in FlyBase
FLIGHTClick here to see CG10693 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10693 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10693
Entrez GeneEntrez Gene page for CG10693
UniprotUniprot page for CG10693

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)