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Gene Page - CG Number : CG10700
Gene Summary - CG10700:

CG10700: This gene is referred to in FlyBase by the symbol Dmel\CG10700 (FBgn0032754). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ferredoxin-NAD(P) reductase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: oxidation-reduction process; cell redox homeostasis. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD/NAD-linked reductase, dimerisation; Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain; Pyridine nucleotide-disulphide oxidoreductase, NAD-binding domain; Pyridine nucleotide-disulphide oxidoreductase, dimerisation; Rieske [2Fe-2S] iron-sulphur domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very low expression to a trough of no expression detected. Peak expression observed during late larval stages, at stages throughout the pupal period, in adult male stages.

Gene summary for CG10700 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10700:CG10700 is not perturbed in primary screen.
CG10700 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10700.
Cell Count:
CG_NumberCategoryR1R2R3
CG10700Primary screen9441122
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10700:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
20136-0.4886611864.3259572024.062334499-0.0215103010.2862551341.6355952712.8268587341.9982556843.3211068930.5125860862.4221478770.7364325490.6114354350.6747445070.3849613750.6974030371.3194636293.2648851572.2179047673.351141057-0.51549279310.105415045.305061806
202190-0.514672065-1.629223629-0.407309139-2.376944462-2.949855268-1.479367426-1.866343053-1.927445707-4.094798025-1.326860682-1.655351714-0.468431221-1.708841781-1.086744849-0.49393397-3.328479707-2.210650093-2.437897143-2.678459885-4.133966319-0.655497984-3.533772606-4.303791552
203100-0.700410373-0.976323062-0.7540102580.1284147-2.23987376-2.557331903-3.375548236-2.403957931-4.037924491-0.946791357-0.450962831-0.287084872-0.776518833-1.138847491-0.86340791-1.96203651-2.688442536-1.995910445-3.177512094-4.655770406-0.850018994-0.952565283-0.489988207
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10700 is not tested in classification assay
Integrated Annotations for CG10700 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
oxidation-reduction processGO:0055114inferred from electronic annotation with InterPro:IPR001327, InterPro:IPR004099, InterPro:IPR013027, InterPro:IPR016156, InterPro:IPR017941, InterPro:IPR023753
cell redox homeostasis
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
cytoplasmGO:0005737inferred from electronic annotation with InterPro:IPR004099
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
ferredoxin-NAD(P) reductase activityGO:0008937inferred from sequence or structural similarity with UniProtKB:O42346
2 iron, 2 sulfur cluster binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10700 in FlyBase
FLIGHTClick here to see CG10700 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10700 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10700
Entrez GeneEntrez Gene page for CG10700
UniprotUniprot page for CG10700

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)