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Gene Page - CG Number : CG10704
Gene Summary - CG10704:

CG10704: The gene twin of eyg is referred to in FlyBase by the symbol Dmel\toe (CG10704, FBgn0036285). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity. There is experimental evidence that it is involved in the biological process: compound eye development; negative regulation of transcription from RNA polymerase II promoter. 7 alleles are reported. The phenotypes of these alleles are annotated with: scutum; scutellum. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Homeobox, conserved site; Homeodomain; Homeodomain-like; Paired domain; Winged helix-turn-helix transcription repressor DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed in adult male stages.

Gene summary for CG10704 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10704:CG10704 is not perturbed in primary screen.
CG10704 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10704.
Cell Count:
CG_NumberCategoryR1R2R3
CG10704Primary screen7671215
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10704:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
20141-0.2690414860.6272320192.5946212370.164865380.3508227861.247619181.6847175811.3948725213.4185824913.5965373255.523535962.9624418011.4216339631.0170925190.7217861120.8224174383.8356632867.4677051433.3072584094.351120015-0.00871240910.316614076.131933189
202185-0.514672065-1.629223629-0.407309139-2.376944462-2.949855268-1.479367426-1.866343053-1.927445707-4.094798025-1.326860682-1.655351714-0.468431221-1.708841781-1.086744849-0.49393397-3.328479707-2.210650093-2.437897143-2.678459885-4.133966319-0.655497984-1.692073997-1.160665325
20395-0.442663541-0.0490790820.193422724-0.270890423-0.736891841-0.556311791-0.281627626-0.413540381-0.603785953-0.8588746260.024015736-0.26007877-0.494686840.080791688-0.395648239-0.846603842-1.233500438-1.103376048-1.437849678-1.0745057152.826428865-0.372265733-0.346874068
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10704 is not tested in classification assay
Integrated Annotations for CG10704 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
regulation of transcription, DNA-dependentGO:0006355inferred from sequence or structural similarity
negative regulation of transcription from RNA polymerase II promoter
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
nucleusGO:0005634inferred from sequence or structural similarity
transcription factor complex
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
sequence-specific DNA binding transcription factor activityGO:0003700inferred from sequence or structural similarity
sequence-specific DNA binding transcription factor activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10704 in FlyBase
FLIGHTClick here to see CG10704 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10704 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10704
Entrez GeneEntrez Gene page for CG10704
UniprotUniprot page for CG10704

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)