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Gene Page - CG Number : CG10711
Gene Summary - CG10711:

CG10711: The gene Vacuolar protein sorting 36 is referred to in FlyBase by the symbol Dmel\Vps36 (CG10711, FBgn0086785). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: mRNA 3'-UTR binding. There is experimental evidence that it is involved in the biological process: regulation of apoptotic process; cell proliferation; regulation of Notch signaling pathway. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: EAP30; Vacuolar protein sorting protein 36, GLUE domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, during early pupal stages.

Gene summary for CG10711 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10711:CG10711 is not perturbed in primary screen.
CG10711 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10711.
Cell Count:
CG_NumberCategoryR1R2R3
CG10711Primary screen84217311
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10711:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
20142-0.077814972-0.0829178993.511994703-0.073908804-0.2361415962.8187299182.7198446671.738921173.7602559871.0054706071.5982226751.6005695883.0384694474.2164709650.617029141-0.3497584942.060977064.5954311022.0686691964.632411704-0.0390136599.7409344995.747383005
2021842.5383962991.496932273-1.121249415-0.685057988-2.380088756-1.345942522-0.905869824-2.831062781-2.829116743-1.788559877-2.1001044931.317476819-0.438475231-1.140407945-0.13498628-2.646390554-0.977818438-1.638394699-0.940260764-1.999944924-1.202418722-0.829307599-1.664723704
203942.8752127431.948616565-0.378533422-0.4592206280.6988345640.2716829280.4027377570.429113338-0.9732959450.9765589491.169957676-0.6690545130.5212302430.2899849752.14562597-0.441407188-0.28447946-0.081083059-0.116279681-0.972026608-0.528614436-0.515262869-0.457191832
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10711 is not tested in classification assay
Integrated Annotations for CG10711 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
regulation of Notch signaling pathwayGO:0008593inferred from expression pattern
regulation of apoptotic process
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
mRNA 3'-UTR bindingGO:0003730inferred from direct assay
phosphatidylinositol-3-phosphate binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10711 in FlyBase
FLIGHTClick here to see CG10711 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10711 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10711
Entrez GeneEntrez Gene page for CG10711
UniprotUniprot page for CG10711

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)