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Gene Page - CG Number : CG10721
Gene Summary - CG10721:

CG10721: This gene is referred to in FlyBase by the symbol Dmel\CG10721 (FBgn0032846). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: oxidoreductase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: oxidation-reduction process. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages.

Gene summary for CG10721 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10721:CG10721 is perturbed in following parameters in primary screen: Tmph1
CG10721 is not tested in classification assay (fluid).
CG10721 is perturbed in following parameters in classification assay (transferrin): CellSize-(tfr) Okt+(tfr) Tint2+ Tint3+ Tnum-
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10721.
Cell Count:
CG_NumberCategoryR1R2R3
CG10721Primary screen72239402
CG10721Secondary assay103511381357
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10721:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
20145-0.2603756191.491115313.011993810.928314985-0.1282318591.1282969913.8672520471.4214035714.0977570792.2390140943.3703004642.7754212091.7120571451.5908540270.097390985-0.1565953424.1836008738.4300615675.4761363145.51983133-0.2166013157.5512188973.942204563
202181-1.062865038-1.2315651140.250161365-0.286886573-2.053114462-0.435048016-1.56402018-0.356493822-1.880971910.705361718-1.0221887812.3773785790.637287765-0.723496596-0.217431156-1.6755398930.1966466690.1756242520.853716669-1.429429271-1.049123402-0.443266026-0.560831019
20391-0.647122425-0.072163882-0.246784238-0.1418585180.379341803-1.039889396-1.312775136-1.1923874471.4678109443.3267646212.038875210.1324296020.998277691.0037876190.20581472.7747438213.7481199252.6676569092.9040142691.304380005-0.479848717-0.357905591-0.144245596
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Transferrin:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10721Slide1F0.9250.9901.1370.898
CG10721Slide1O0.0151.3881.2641.485
CG10721Slide1T0.5260.9800.7971.045
F=Fdex; O=Surface TfR (Okt9); T=Tf

Integrated Annotations for CG10721 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
oxidation-reduction processGO:0055114inferred from electronic annotation with InterPro:IPR013027, InterPro:IPR023753
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
oxidoreductase activityGO:0016491inferred from sequence or structural similarity with EMBL:Z54327; protein_id:CAA91121
Other annotations
DatabaseLink
FlyBaseClick here to see CG10721 in FlyBase
FLIGHTClick here to see CG10721 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10721 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10721
Entrez GeneEntrez Gene page for CG10721
UniprotUniprot page for CG10721

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)