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Gene Page - CG Number : CG10725
Gene Summary - CG10725:

CG10725: This gene is referred to in FlyBase by the symbol Dmel\CG10725 (FBgn0036362). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: structural constituent of peritrophic membrane. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: chitin metabolic process. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Chitin binding domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed within 18-24 hour embryonic stages, at stages throughout the larval period.

Gene summary for CG10725 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10725:CG10725 is perturbed in following parameters in primary screen: Fint2
CG10725 is perturbed in following parameters in classification assay (fluid): LP_Fnum- SP_Fint4- SP_Fnum-
CG10725 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10725.
Cell Count:
CG_NumberCategoryR1R2R3
CG10725Primary screen52971422
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10725:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201470.769374675.6318556762.846794049-0.4111542980.1589186940.4624986991.5922301070.5822663710.640610132-0.409853769-0.263940969-0.8531452780.185776484-0.186931018-0.344418677-0.1868502340.185747793-1.18184934-0.7776481151.285370810.539459295-0.682118444-0.168264978
2022095.5724516753.6314078880.8716973930.917610724-1.587522262-1.0577102851.822340315-0.934852009-0.998176828-1.220643183-1.1172499530.4254759651.6699322475.567738204-0.498046055-1.5560038370.4776523290.086004685-1.349917857-0.413594516-1.1307257210.574926967-0.676159325
2031191.4741266870.5634093492.400121467-0.142612122.0039680823.2761188036.1553106262.0541244172.1737745490.619958510.717710307-0.0796028251.1277656691.4934612480.8655984980.9309559241.1347311180.4445295871.7769970842.8630562340.2515596510.7066252151.130037997
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10725Slide20C0.6500.7731.1711.315
CG10725Slide20O0.8140.9171.1391.028
CG10725Slide20P0.9560.9221.0211.048
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG10725 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
chitin metabolic processGO:0006030inferred from electronic annotation with InterPro:IPR002557
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
extracellular regionGO:0005576inferred from electronic annotation with InterPro:IPR002557
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
structural constituent of peritrophic membraneGO:0016490inferred from sequence or structural similarity with EMBL:AF026492
chitin binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10725 in FlyBase
FLIGHTClick here to see CG10725 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10725 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10725
Entrez GeneEntrez Gene page for CG10725
UniprotUniprot page for CG10725

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)