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Gene Page - CG Number : CG10738
Gene Summary - CG10738:

CG10738: This gene is referred to in FlyBase by the symbol Dmel\CG10738 (FBgn0036368). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: receptor activity; guanylate cyclase activity. There is experimental evidence that it is involved in the biological process: Golgi organization; positive regulation of cell proliferation; negative regulation of cell size; positive regulation of mitotic cell cycle. 6 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Adenylyl cyclase class-3/4/guanylyl cyclase; Adenylyl cyclase class-3/4/guanylyl cyclase, conserved site; Extracellular ligand-binding receptor; Haem NO binding associated; Protein kinase, catalytic domain; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase catalytic domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages, during late pupal stages.

Gene summary for CG10738 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10738:CG10738 is not perturbed in primary screen.
CG10738 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10738.
Cell Count:
CG_NumberCategoryR1R2R3
CG10738Primary screen477294534
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10738:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201520.1955344082.8466375934.2050890351.5851420780.2287908540.243020090.6070514720.3669120880.7673843340.3282810661.217683877-0.893721974-0.529715662-0.54683456-0.3535897750.022522203-0.264781331-0.101144656-0.3165340672.2497856061.1750937893.5610460062.706653436
202204-0.678968055-0.24863528-0.0632284110.185195658-0.3096656410.510203561.6225111770.2810787740.630251926-0.300019660.0998066660.3761185740.305751259-0.2925455510.305268381-0.333287378-0.2826419840.982400286-0.5190077461.02436014-0.3251573341.292635504-0.11768803
2031140.508747134-0.0086745840.0304556670.5333705661.6554764721.7479656292.151162281.8567467342.0612260181.81572931.2157054950.5452508752.4853359671.566561297-0.4692537771.1779334361.2785777160.5482429061.5066931492.047124799-0.171173175-0.4052623470.339769361
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10738 is not tested in classification assay
Integrated Annotations for CG10738 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
signal transductionGO:0007165inferred from sequence or structural similarity
Golgi organization
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
plasma membraneGO:0005886inferred from sequence or structural similarity
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
guanylate cyclase activityGO:0004383inferred from sequence or structural similarity
receptor activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10738 in FlyBase
FLIGHTClick here to see CG10738 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10738 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10738
Entrez GeneEntrez Gene page for CG10738
UniprotUniprot page for CG10738

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)