.:: RNAiDB - Gene Page ::. Gene Page - CG Number : CG10738Gene Summary - CG10738:CG10738: This gene is referred to in FlyBase by the symbol Dmel\CG10738 (FBgn0036368). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: receptor activity; guanylate cyclase activity. There is experimental evidence that it is involved in the biological process: Golgi organization; positive regulation of cell proliferation; negative regulation of cell size; positive regulation of mitotic cell cycle. 6 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Adenylyl cyclase class-3/4/guanylyl cyclase; Adenylyl cyclase class-3/4/guanylyl cyclase, conserved site; Extracellular ligand-binding receptor; Haem NO binding associated; Protein kinase, catalytic domain; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase catalytic domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages, during late pupal stages. Gene summary for CG10738 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)Experimental Summary - CG10738:CG10738 is not perturbed in primary screen. CG10738 is not tested in classification assay. Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10738.Cell Count:CG_NumberCategoryR1R2R3CG10738Primary screen477294534R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3Primary screen data - CG10738: SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize201520.1955344082.8466375934.2050890351.5851420780.2287908540.243020090.6070514720.3669120880.7673843340.3282810661.217683877-0.893721974-0.529715662-0.54683456-0.3535897750.022522203-0.264781331-0.101144656-0.3165340672.2497856061.1750937893.5610460062.706653436202204-0.678968055-0.24863528-0.0632284110.185195658-0.3096656410.510203561.6225111770.2810787740.630251926-0.300019660.0998066660.3761185740.305751259-0.2925455510.305268381-0.333287378-0.2826419840.982400286-0.5190077461.02436014-0.3251573341.292635504-0.117688032031140.508747134-0.0086745840.0304556670.5333705661.6554764721.7479656292.151162281.8567467342.0612260181.81572931.2157054950.5452508752.4853359671.566561297-0.4692537771.1779334361.2785777160.5482429061.5066931492.047124799-0.171173175-0.4052623470.339769361 SN: Slide Number; RN: Replicate Number; WN: Well NumberExperimental Data (Classification Assay):CG10738 is not tested in classification assayIntegrated Annotations for CG10738 :Gene Ontology Annoations: Biological ProcessBiological Process - TermGO IDEvidencesignal transductionGO:0007165inferred from sequence or structural similarity Golgi organizationGene Ontology Annoations: Cellular ComponentCellular Component - TermGO IDEvidenceplasma membraneGO:0005886inferred from sequence or structural similarityGene Ontology Annoations: Molecular FunctionMolecular Function - TermGO IDEvidenceguanylate cyclase activityGO:0004383inferred from sequence or structural similarity receptor activity Other annotations DatabaseLinkFlyBaseClick here to see CG10738 in FlyBaseFLIGHTClick here to see CG10738 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)BioGRIDClick here to see CG10738 in BioGRID (Interaction Summary)Off-targetClick here for Off-target data for CG10738Entrez GeneEntrez Gene page for CG10738UniprotUniprot page for CG10738 Endosite Team : Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in) Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)
.:: RNAiDB - Gene Page ::. Gene Page - CG Number : CG10738Gene Summary - CG10738:CG10738: This gene is referred to in FlyBase by the symbol Dmel\CG10738 (FBgn0036368). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: receptor activity; guanylate cyclase activity. There is experimental evidence that it is involved in the biological process: Golgi organization; positive regulation of cell proliferation; negative regulation of cell size; positive regulation of mitotic cell cycle. 6 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Adenylyl cyclase class-3/4/guanylyl cyclase; Adenylyl cyclase class-3/4/guanylyl cyclase, conserved site; Extracellular ligand-binding receptor; Haem NO binding associated; Protein kinase, catalytic domain; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase catalytic domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages, during late pupal stages. Gene summary for CG10738 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)Experimental Summary - CG10738:CG10738 is not perturbed in primary screen. CG10738 is not tested in classification assay. Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10738.Cell Count:CG_NumberCategoryR1R2R3CG10738Primary screen477294534R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3Primary screen data - CG10738: SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize201520.1955344082.8466375934.2050890351.5851420780.2287908540.243020090.6070514720.3669120880.7673843340.3282810661.217683877-0.893721974-0.529715662-0.54683456-0.3535897750.022522203-0.264781331-0.101144656-0.3165340672.2497856061.1750937893.5610460062.706653436202204-0.678968055-0.24863528-0.0632284110.185195658-0.3096656410.510203561.6225111770.2810787740.630251926-0.300019660.0998066660.3761185740.305751259-0.2925455510.305268381-0.333287378-0.2826419840.982400286-0.5190077461.02436014-0.3251573341.292635504-0.117688032031140.508747134-0.0086745840.0304556670.5333705661.6554764721.7479656292.151162281.8567467342.0612260181.81572931.2157054950.5452508752.4853359671.566561297-0.4692537771.1779334361.2785777160.5482429061.5066931492.047124799-0.171173175-0.4052623470.339769361 SN: Slide Number; RN: Replicate Number; WN: Well NumberExperimental Data (Classification Assay):CG10738 is not tested in classification assayIntegrated Annotations for CG10738 :Gene Ontology Annoations: Biological ProcessBiological Process - TermGO IDEvidencesignal transductionGO:0007165inferred from sequence or structural similarity Golgi organizationGene Ontology Annoations: Cellular ComponentCellular Component - TermGO IDEvidenceplasma membraneGO:0005886inferred from sequence or structural similarityGene Ontology Annoations: Molecular FunctionMolecular Function - TermGO IDEvidenceguanylate cyclase activityGO:0004383inferred from sequence or structural similarity receptor activity Other annotations DatabaseLinkFlyBaseClick here to see CG10738 in FlyBaseFLIGHTClick here to see CG10738 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)BioGRIDClick here to see CG10738 in BioGRID (Interaction Summary)Off-targetClick here for Off-target data for CG10738Entrez GeneEntrez Gene page for CG10738UniprotUniprot page for CG10738
CG10738: This gene is referred to in FlyBase by the symbol Dmel\CG10738 (FBgn0036368). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: receptor activity; guanylate cyclase activity. There is experimental evidence that it is involved in the biological process: Golgi organization; positive regulation of cell proliferation; negative regulation of cell size; positive regulation of mitotic cell cycle. 6 alleles are reported. No phenotypic data is available. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Adenylyl cyclase class-3/4/guanylyl cyclase; Adenylyl cyclase class-3/4/guanylyl cyclase, conserved site; Extracellular ligand-binding receptor; Haem NO binding associated; Protein kinase, catalytic domain; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase catalytic domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages, during late pupal stages.
Endosite Team : Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in) Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)