Gene Page - CG Number : CG10742

Gene Summary - CG10742:

CG10742: The gene Tetraspanin 3A is referred to in FlyBase by the symbol Dmel\Tsp3A (CG10742, FBgn0040334). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: border follicle cell migration; positive regulation of Notch signaling pathway; phagocytosis, engulfment. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Tetraspanin; Tetraspanin, EC2 domain; Tetraspanin/Peripherin. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, during early pupal stages.

Gene summary for CG10742 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)

Experimental Summary - CG10742:

CG10742 is not perturbed in primary screen.
CG10742 is not tested in classification assay.

Cellular phenotyping(Images):

Click here to access phenotyping images of gene CG10742.

Cell Count:

CG_Number	Category	R1	R2	R3
CG10742	Primary screen	593	286	517

R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3

Primary screen data - CG10742:

SN	RN	WN	Fint1	Fint2	Fint3	Fint4	Fnum	Fmph1	Fmph2	Fmph3	Fclc	Tint1	Tint2	Tint3	Tint4	Rto1	Rto2	Rto3	Okt	Tnum	Tmph1	Tmph2	Tmph3	Tclc	CellSize
20	1	53	-0.544324601	1.718209492	-0.389478409	-0.296521422	0.579563957	0.740456489	-0.119960153	0.570962445	0.070440128	0.008673726	0.153065276	0.646464276	-0.194042215	-1.043214753	0.432960579	-0.325998276	-1.588068491	0.630769859	-2.714552735	-0.365306877	0.442512872	0.298440805	-0.445114874
20	2	203	0.451471004	0.526333457	0.424398552	-0.356675943	-0.209828188	-0.098628629	1.335464691	-0.177504688	0.429885761	0.222392803	0.656669229	-0.312672606	1.044640421	0.270859904	-0.221339142	-0.417105729	0.812579455	0.854160478	0.172735214	0.761501097	-0.699274663	-0.543385898	-0.025912153
20	3	113	0.176925405	0.413840484	-0.506080283	-0.528928886	1.430780724	1.633444848	1.694647016	1.756999746	1.068520244	-0.361553288	1.484607294	-0.402003095	0.139309295	-0.251571707	-0.032436573	0.063345477	-0.214915439	0.921864892	-0.10617109	1.067091529	0.019781946	-0.519738818	0.550041346

SN: Slide Number; RN: Replicate Number; WN: Well Number

Experimental Data (Classification Assay):

CG10742 is not tested in classification assay

Integrated Annotations for CG10742 :

Gene Ontology Annoations: Biological Process

Biological Process - Term	GO ID	Evidence
phagocytosis, engulfment	GO:0006911	inferred from mutant phenotype

Gene Ontology Annoations: Cellular Component

Cellular Component - Term	GO ID	Evidence
integral to membrane	GO:0016021	inferred from sequence or structural similarity integral to membrane

Gene Ontology Annoations: Molecular Function

Molecular Function - Term	GO ID	Evidence
molecular_function	GO:0003674	no biological data available

Other annotations

Database	Link
FlyBase	Click here to see CG10742 in FlyBase
FLIGHT	Click here to see CG10742 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRID	Click here to see CG10742 in BioGRID (Interaction Summary)
Off-target	Click here for Off-target data for CG10742
Entrez Gene	Entrez Gene page for CG10742
Uniprot	Uniprot page for CG10742

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Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)