Gene Page - CG Number : CG10743

Gene Summary - CG10743:

CG10743: The gene Liprin-β is referred to in FlyBase by the symbol Dmel\Liprin-β (CG10743, FBgn0036376). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; protein homodimerization activity. There is experimental evidence that it is involved in the biological process: synaptic growth at neuromuscular junction; axon target recognition. 14 alleles are reported. The phenotypes of these alleles are annotated with: photoreceptor cell R7; medulla. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Sterile alpha motif domain; Sterile alpha motif, type 1; Sterile alpha motif, type 2; Sterile alpha motif/pointed domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.

Gene summary for CG10743 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)

Experimental Summary - CG10743:

CG10743 is not perturbed in primary screen.
CG10743 is not tested in classification assay.

Cellular phenotyping(Images):

Click here to access phenotyping images of gene CG10743.

Cell Count:

CG_Number	Category	R1	R2	R3
CG10743	Primary screen	454	256	354

R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3

Primary screen data - CG10743:

SN	RN	WN	Fint1	Fint2	Fint3	Fint4	Fnum	Fmph1	Fmph2	Fmph3	Fclc	Tint1	Tint2	Tint3	Tint4	Rto1	Rto2	Rto3	Okt	Tnum	Tmph1	Tmph2	Tmph3	Tclc	CellSize
20	1	54	-0.064587198	0.805826533	1.943824819	0.213722814	-0.485612737	0.011326022	0.069758079	0.102704198	-0.867956605	-0.281001142	-0.977338094	-0.009245773	0.988406297	1.236213656	-0.551095956	-0.512200735	-2.226111541	-0.967434386	-2.457567874	-0.312355786	0.783151586	0.64978593	0.85071467
20	2	202	-0.049150267	-0.491640093	0.494685646	-0.304291229	-0.272925761	-0.077609875	1.343856322	-0.248847061	0.363964185	-0.186625769	0.348356819	0.165984862	0.181102788	-0.127117849	-0.305673748	-0.574687246	1.252756314	0.525861034	-0.186713521	0.440842711	-0.650174273	0.126377295	-0.766495295
20	3	112	1.888142944	4.82120216	4.904841169	0.332318726	1.264869144	2.869116837	6.305651048	1.581958443	2.147566553	1.303099066	2.16434788	-0.359937718	1.838395595	1.552812592	-0.054720125	1.490895653	1.216367754	1.093637953	1.178558155	3.108359237	0.847204111	-0.68028139	-0.418049559

SN: Slide Number; RN: Replicate Number; WN: Well Number

Experimental Data (Classification Assay):

CG10743 is not tested in classification assay

Integrated Annotations for CG10743 :

Gene Ontology Annoations: Biological Process

Biological Process - Term	GO ID	Evidence
axon target recognition	GO:0007412	inferred from mutant phenotype synaptic growth at neuromuscular junction

Gene Ontology Annoations: Cellular Component

Cellular Component - Term	GO ID	Evidence
protein complex	GO:0043234	inferred from direct assay

Gene Ontology Annoations: Molecular Function

Molecular Function - Term	GO ID	Evidence
protein homodimerization activity	GO:0042803	inferred from physical interaction with Liprin-β protein binding

Other annotations

Database	Link
FlyBase	Click here to see CG10743 in FlyBase
FLIGHT	Click here to see CG10743 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRID	Click here to see CG10743 in BioGRID (Interaction Summary)
Off-target	Click here for Off-target data for CG10743
Entrez Gene	Entrez Gene page for CG10743
Uniprot	Uniprot page for CG10743

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Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)