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Gene Page - CG Number : CG10743
Gene Summary - CG10743:

CG10743: The gene Liprin-β is referred to in FlyBase by the symbol Dmel\Liprin-β (CG10743, FBgn0036376). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; protein homodimerization activity. There is experimental evidence that it is involved in the biological process: synaptic growth at neuromuscular junction; axon target recognition. 14 alleles are reported. The phenotypes of these alleles are annotated with: photoreceptor cell R7; medulla. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Sterile alpha motif domain; Sterile alpha motif, type 1; Sterile alpha motif, type 2; Sterile alpha motif/pointed domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages.

Gene summary for CG10743 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10743:CG10743 is not perturbed in primary screen.
CG10743 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10743.
Cell Count:
CG_NumberCategoryR1R2R3
CG10743Primary screen454256354
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10743:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
20154-0.0645871980.8058265331.9438248190.213722814-0.4856127370.0113260220.0697580790.102704198-0.867956605-0.281001142-0.977338094-0.0092457730.9884062971.236213656-0.551095956-0.512200735-2.226111541-0.967434386-2.457567874-0.3123557860.7831515860.649785930.85071467
202202-0.049150267-0.4916400930.494685646-0.304291229-0.272925761-0.0776098751.343856322-0.2488470610.363964185-0.1866257690.3483568190.1659848620.181102788-0.127117849-0.305673748-0.5746872461.2527563140.525861034-0.1867135210.440842711-0.6501742730.126377295-0.766495295
2031121.8881429444.821202164.9048411690.3323187261.2648691442.8691168376.3056510481.5819584432.1475665531.3030990662.16434788-0.3599377181.8383955951.552812592-0.0547201251.4908956531.2163677541.0936379531.1785581553.1083592370.847204111-0.68028139-0.418049559
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10743 is not tested in classification assay
Integrated Annotations for CG10743 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
axon target recognitionGO:0007412inferred from mutant phenotype
synaptic growth at neuromuscular junction
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
protein complexGO:0043234inferred from direct assay
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
protein homodimerization activityGO:0042803inferred from physical interaction with Liprin-β
protein binding
Other annotations
DatabaseLink
FlyBaseClick here to see CG10743 in FlyBase
FLIGHTClick here to see CG10743 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10743 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10743
Entrez GeneEntrez Gene page for CG10743
UniprotUniprot page for CG10743

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)