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Gene Page - CG Number : CG10751
Gene Summary - CG10751:

CG10751: The gene roadblock is referred to in FlyBase by the symbol Dmel\robl (CG10751, FBgn0024196). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ATPase activity, coupled. There is experimental evidence that it is involved in the biological process: dendrite morphogenesis; mushroom body development. 12 alleles are reported. The phenotypes of these alleles are annotated with: segmental nerve; eye; mitotic telophase; trichogen cell; mitotic cell cycle; macrochaeta; mitotic anaphase; imaginal disc. It has one annotated transcript and one annotated polypeptide. Protein features are: Dynein light chain, roadblock-type; Dynein light chain-related. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-12 hour embryonic stages.

Gene summary for CG10751 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10751:CG10751 is not perturbed in primary screen.
CG10751 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10751.
Cell Count:
CG_NumberCategoryR1R2R3
CG10751Primary screen53017777
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10751:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
20158-0.3981506940.9812615210.825871241-0.744026802-0.5258660610.3642422641.1345719970.8144003810.7853220540.199677120.0246164781.486441652-1.437906127-0.32347769-0.324308350.0442929-1.209464092-0.737661074-1.027803990.850124910.6325145262.5278239060.947251425
2021980.4979349750.096747570.3933901050.177444648-0.83510434-0.840618230.747728811-0.973479521-0.323828199-0.3202326980.0226358360.2011644390.090142599-0.386201617-1.0804359830.0389969080.9635606180.6681422920.385640874-0.196587031-0.75954367-0.875285547-0.627241421
203108-0.127741775-1.355277868-0.935562936-1.61989828-3.340455472-3.823291272-4.376276463-3.376264763-3.3216586790.042601189-0.91452857-0.556907226-0.296379012-0.6753306920.017220315-1.628071511-1.1533044250.375083824-1.564168213-4.3469466320.5109161130.52384510.024390079
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10751 is not tested in classification assay
Integrated Annotations for CG10751 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
microtubule-based movementGO:0007018inferred from sequence or structural similarity
mushroom body development
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
axonemal dynein complexGO:0005858non-traceable author statement
dynein complex
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
ATPase activity, coupledGO:0042623inferred from sequence or structural similarity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10751 in FlyBase
FLIGHTClick here to see CG10751 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10751 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10751
Entrez GeneEntrez Gene page for CG10751
UniprotUniprot page for CG10751

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)