.:: RNAiDB - Gene Page ::. Gene Page - CG Number : CG10772Gene Summary - CG10772:CG10772: The gene Furin 1 is referred to in FlyBase by the symbol Dmel\Fur1 (CG10772, FBgn0004509). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: serine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process: synaptic target recognition. 33 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has 9 annotated transcripts and 9 annotated polypeptides. Protein features are: Furin-like repeat; Galactose-binding domain-like; Growth factor, receptor; Peptidase S8, subtilisin, Asp-active site; Peptidase S8, subtilisin, His-active site; Peptidase S8, subtilisin, Ser-active site; Peptidase S8, subtilisin-related; Peptidase S8/S53, subtilisin/kexin/sedolisin; Proprotein convertase, P; Proteinase inhibitor, propeptide. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 and 12-24 hour embryonic stages, during early pupal stages, in adult female stages. Gene summary for CG10772 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)Experimental Summary - CG10772:CG10772 is not perturbed in primary screen. CG10772 is not tested in classification assay. Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10772.Cell Count:CG_NumberCategoryR1R2R3CG10772Primary screen7028250R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3Primary screen data - CG10772: SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize20168-0.5532020590.619777985-0.168364553-0.5937836381.0688337830.5528232310.0138038990.9431642381.648695780.1640955570.101408175-0.4112851780.3460479850.295494069-0.2940953011.1131250780.9802003650.1488699361.0687049451.613175661-0.2677630333.7249907392.400929619202218-0.317520094-1.818688491-1.006765089-0.187746385-3.343121482-2.545713311-2.979440225-1.653918053-3.612314094-0.523808208-1.8982049910.094416728-0.896193514-1.2840996330.105414473-2.517611506-1.006885178-1.915215191-0.73344609-3.024980136-1.768616016-1.979802364-1.910791444203681.5205905322.1036525492.4158926490.014914443-0.1896554790.322124533.449241557-0.0250774320.346796150.7959346131.740434783-0.54357274-1.010268797-0.1820540140.429618991.8666691511.2256492951.0085947250.0877605440.415271298-0.595476461-0.4270825290.294464552 SN: Slide Number; RN: Replicate Number; WN: Well NumberExperimental Data (Classification Assay):CG10772 is not tested in classification assayIntegrated Annotations for CG10772 :Gene Ontology Annoations: Biological ProcessBiological Process - TermGO IDEvidenceproteolysisGO:0006508non-traceable author statement proteolysisGene Ontology Annoations: Cellular ComponentCellular Component - TermGO IDEvidenceplasma membraneGO:0005886inferred from sequence or structural similarity plasma membraneGene Ontology Annoations: Molecular FunctionMolecular Function - TermGO IDEvidenceserine-type endopeptidase activityGO:0004252inferred from direct assay serine-type endopeptidase activity Other annotations DatabaseLinkFlyBaseClick here to see CG10772 in FlyBaseFLIGHTClick here to see CG10772 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)BioGRIDClick here to see CG10772 in BioGRID (Interaction Summary)Off-targetClick here for Off-target data for CG10772Entrez GeneEntrez Gene page for CG10772UniprotUniprot page for CG10772 Endosite Team : Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in) Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)
.:: RNAiDB - Gene Page ::. Gene Page - CG Number : CG10772Gene Summary - CG10772:CG10772: The gene Furin 1 is referred to in FlyBase by the symbol Dmel\Fur1 (CG10772, FBgn0004509). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: serine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process: synaptic target recognition. 33 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has 9 annotated transcripts and 9 annotated polypeptides. Protein features are: Furin-like repeat; Galactose-binding domain-like; Growth factor, receptor; Peptidase S8, subtilisin, Asp-active site; Peptidase S8, subtilisin, His-active site; Peptidase S8, subtilisin, Ser-active site; Peptidase S8, subtilisin-related; Peptidase S8/S53, subtilisin/kexin/sedolisin; Proprotein convertase, P; Proteinase inhibitor, propeptide. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 and 12-24 hour embryonic stages, during early pupal stages, in adult female stages. Gene summary for CG10772 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)Experimental Summary - CG10772:CG10772 is not perturbed in primary screen. CG10772 is not tested in classification assay. Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10772.Cell Count:CG_NumberCategoryR1R2R3CG10772Primary screen7028250R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3Primary screen data - CG10772: SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize20168-0.5532020590.619777985-0.168364553-0.5937836381.0688337830.5528232310.0138038990.9431642381.648695780.1640955570.101408175-0.4112851780.3460479850.295494069-0.2940953011.1131250780.9802003650.1488699361.0687049451.613175661-0.2677630333.7249907392.400929619202218-0.317520094-1.818688491-1.006765089-0.187746385-3.343121482-2.545713311-2.979440225-1.653918053-3.612314094-0.523808208-1.8982049910.094416728-0.896193514-1.2840996330.105414473-2.517611506-1.006885178-1.915215191-0.73344609-3.024980136-1.768616016-1.979802364-1.910791444203681.5205905322.1036525492.4158926490.014914443-0.1896554790.322124533.449241557-0.0250774320.346796150.7959346131.740434783-0.54357274-1.010268797-0.1820540140.429618991.8666691511.2256492951.0085947250.0877605440.415271298-0.595476461-0.4270825290.294464552 SN: Slide Number; RN: Replicate Number; WN: Well NumberExperimental Data (Classification Assay):CG10772 is not tested in classification assayIntegrated Annotations for CG10772 :Gene Ontology Annoations: Biological ProcessBiological Process - TermGO IDEvidenceproteolysisGO:0006508non-traceable author statement proteolysisGene Ontology Annoations: Cellular ComponentCellular Component - TermGO IDEvidenceplasma membraneGO:0005886inferred from sequence or structural similarity plasma membraneGene Ontology Annoations: Molecular FunctionMolecular Function - TermGO IDEvidenceserine-type endopeptidase activityGO:0004252inferred from direct assay serine-type endopeptidase activity Other annotations DatabaseLinkFlyBaseClick here to see CG10772 in FlyBaseFLIGHTClick here to see CG10772 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)BioGRIDClick here to see CG10772 in BioGRID (Interaction Summary)Off-targetClick here for Off-target data for CG10772Entrez GeneEntrez Gene page for CG10772UniprotUniprot page for CG10772
CG10772: The gene Furin 1 is referred to in FlyBase by the symbol Dmel\Fur1 (CG10772, FBgn0004509). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: serine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process: synaptic target recognition. 33 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has 9 annotated transcripts and 9 annotated polypeptides. Protein features are: Furin-like repeat; Galactose-binding domain-like; Growth factor, receptor; Peptidase S8, subtilisin, Asp-active site; Peptidase S8, subtilisin, His-active site; Peptidase S8, subtilisin, Ser-active site; Peptidase S8, subtilisin-related; Peptidase S8/S53, subtilisin/kexin/sedolisin; Proprotein convertase, P; Proteinase inhibitor, propeptide. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 and 12-24 hour embryonic stages, during early pupal stages, in adult female stages.
Endosite Team : Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in) Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)