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Gene Page - CG Number : CG10772
Gene Summary - CG10772:

CG10772: The gene Furin 1 is referred to in FlyBase by the symbol Dmel\Fur1 (CG10772, FBgn0004509). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: serine-type endopeptidase activity. There is experimental evidence that it is involved in the biological process: synaptic target recognition. 33 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has 9 annotated transcripts and 9 annotated polypeptides. Protein features are: Furin-like repeat; Galactose-binding domain-like; Growth factor, receptor; Peptidase S8, subtilisin, Asp-active site; Peptidase S8, subtilisin, His-active site; Peptidase S8, subtilisin, Ser-active site; Peptidase S8, subtilisin-related; Peptidase S8/S53, subtilisin/kexin/sedolisin; Proprotein convertase, P; Proteinase inhibitor, propeptide. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-06 and 12-24 hour embryonic stages, during early pupal stages, in adult female stages.

Gene summary for CG10772 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10772:CG10772 is not perturbed in primary screen.
CG10772 is not tested in classification assay.
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10772.
Cell Count:
CG_NumberCategoryR1R2R3
CG10772Primary screen7028250
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10772:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
20168-0.5532020590.619777985-0.168364553-0.5937836381.0688337830.5528232310.0138038990.9431642381.648695780.1640955570.101408175-0.4112851780.3460479850.295494069-0.2940953011.1131250780.9802003650.1488699361.0687049451.613175661-0.2677630333.7249907392.400929619
202218-0.317520094-1.818688491-1.006765089-0.187746385-3.343121482-2.545713311-2.979440225-1.653918053-3.612314094-0.523808208-1.8982049910.094416728-0.896193514-1.2840996330.105414473-2.517611506-1.006885178-1.915215191-0.73344609-3.024980136-1.768616016-1.979802364-1.910791444
203681.5205905322.1036525492.4158926490.014914443-0.1896554790.322124533.449241557-0.0250774320.346796150.7959346131.740434783-0.54357274-1.010268797-0.1820540140.429618991.8666691511.2256492951.0085947250.0877605440.415271298-0.595476461-0.4270825290.294464552
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):CG10772 is not tested in classification assay
Integrated Annotations for CG10772 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
proteolysisGO:0006508non-traceable author statement
proteolysis
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
plasma membraneGO:0005886inferred from sequence or structural similarity
plasma membrane
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
serine-type endopeptidase activityGO:0004252inferred from direct assay
serine-type endopeptidase activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10772 in FlyBase
FLIGHTClick here to see CG10772 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10772 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10772
Entrez GeneEntrez Gene page for CG10772
UniprotUniprot page for CG10772

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)