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Gene Page - CG Number : CG10778
Gene Summary - CG10778:

CG10778: This gene is referred to in FlyBase by the symbol Dmel\CG10778 (FBgn0029980). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: transferase activity, transferring alkyl or aryl (other than methyl) groups. There is experimental evidence that it is involved in the biological process: phagocytosis, engulfment. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Di-trans-poly-cis-decaprenylcistransferase-like; Di-trans-poly-cis-decaprenylcistransferase-like, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 and 18-24 hour embryonic stages, during early larval stages, in adult female stages.

Gene summary for CG10778 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10778:CG10778 is perturbed in following parameters in primary screen: Fint2 Fint3 Fint4 Fmph2 Rto3 Tint2 Tint3 Tmph1 Tmph2 Tmph3
CG10778 is perturbed in following parameters in classification assay (fluid): CellSize-(fld) LP_Fclc- LP_Fint1- LP_Fint2- LP_Fint3- LP_Fmph1- LP_Fmph3- LP_Fnum- NuSize-(fld) Okt+(fld) Rto1+ SP_Fclc- SP_Fint2- SP_Fint3- SP_Fmph2- SP_Fnum-
CG10778 is perturbed in following parameters in classification assay (transferrin): CellSize-(tfr) Fclc- Fint1- Fint2- Fint3- Fint4- Fmph1- Fmph2- Fmph3- Fnum- NuCellD+(tfr) NuSize-(tfr) Okt+(tfr) Rto1-(tfr) Rto2-(tfr) Rto3-(tfr) Tclc- Tint1- Tint2- Tint3- Tint4-
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10778.
Cell Count:
CG_NumberCategoryR1R2R3
CG10778Primary screen60912146
CG10778Secondary assay956575963
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10778:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
201712.5504218487.50353694211.697220593.301740434-0.639617283.2175100954.1967559443.9226116449.30096817910.154472352.7953258284.3673485096.4893014865.7120286810.7482922512.04820448711.6582321415.7801177115.87059689.953308918-0.2643973014.3252735623.067332008
202215-0.869106388-1.4445042520.225121216-0.627439208-2.593441269-1.648938944-1.796061668-2.503863045-3.802015515-1.149980524-2.620942088-1.075585544-1.304970492-1.984660221-1.050517738-2.693694964-2.504598369-2.645838579-2.051090231-2.771465983-0.967821781-1.354826632-1.451499401
203655.52344751510.6542074211.272687373.0736353080.9939581871.2918940815.0580026160.811200848-0.0708984326.0283450780.192810842-0.4890602852.7486283863.82934773-0.2700370193.9148693834.4446662813.4472831383.3614326750.604516089-0.372259364-0.4676017150.294792737
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10778Slide10C0.0050.8270.7120.772
CG10778Slide10O0.0231.2071.1411.090
CG10778Slide10P0.0260.7100.5910.832
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse


Transferrin:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10778Slide1F0.0000.3980.4020.401
CG10778Slide1O0.0101.2451.2431.133
CG10778Slide1T0.0030.5410.3010.411
F=Fdex; O=Surface TfR (Okt9); T=Tf

Integrated Annotations for CG10778 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
phagocytosis, engulfmentGO:0006911inferred from mutant phenotype
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
-
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
transferase activity, transferring alkyl or aryl (other than methyl) groupsGO:0016765inferred from electronic annotation with InterPro:IPR001441, InterPro:IPR018520
Other annotations
DatabaseLink
FlyBaseClick here to see CG10778 in FlyBase
FLIGHTClick here to see CG10778 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10778 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10778
Entrez GeneEntrez Gene page for CG10778
UniprotUniprot page for CG10778

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)