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Gene Page - CG Number : CG10804
Gene Summary - CG10804:

CG10804: This gene is referred to in FlyBase by the symbol Dmel\CG10804 (FBgn0029663). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: neurotransmitter:sodium symporter activity; neurotransmitter transporter activity. Based on sequence similarity, it is predicted to be involved in the biological process: neurotransmitter transport. 3 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: Sodium:neurotransmitter symporter. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.

Gene summary for CG10804 is obtained from FlyBase (FB2013_01, released January 23rd, 2013)
Experimental Summary - CG10804:CG10804 is perturbed in following parameters in primary screen: Fmph2 Fmph3 Okt Rto2 Tmph2
CG10804 is perturbed in following parameters in classification assay (fluid): LP_Fclc- LP_Fint1- LP_Fint2- LP_Fint3- LP_Fint4+ LP_Fmph1- LP_Fmph2- LP_Fmph3- LP_Fnum- NuSize-(fld) Okt+(fld) Rto1+ Rto2+ Rto3+ SP_Fclc- SP_Fint2- SP_Fint3- SP_Fmph1- SP_Fmph2- SP_Fmph3- SP_Fnum-
CG10804 is not tested in classification assay (transferrin).
Cellular phenotyping(Images): Click here to access phenotyping images of gene CG10804.
Cell Count:
CG_NumberCategoryR1R2R3
CG10804Primary screen333888613
R1: Replicate No. 1; R2: Replicate No.2; R3: Replicate No. 3
Primary screen data - CG10804:
SNRNWNFint1Fint2Fint3Fint4FnumFmph1Fmph2Fmph3FclcTint1Tint2Tint3Tint4Rto1Rto2Rto3OktTnumTmph1Tmph2Tmph3TclcCellSize
2017716.6764057919.2993417321.5259761-1.3847812423.90339685312.681906717.0753021193.952766422-5.10920912930.38146963-0.774107122.0995841715.5876201043.28210043319.867170686.38540105210.177998179.2488295032.0787944870.62775459412.32428217-0.182602448-0.845503459
2022390.700997795-0.093466555-0.234354978-0.231168461.6146789932.7100690293.0717572573.1466429873.4961978731.0235826964.490375567-0.4980676613.3257373922.3825889923.5830641751.6266849911.6457838713.7772924651.6493843944.3345032451.2093660059.4235670433.35915792
20389-0.3637912571.7447890760.431588309-0.5068966970.6882016971.5466315420.2462964161.754825920.390830921-0.482639578-0.2253894550.169080511-0.405322417-0.4204194710.67800260.27257462-0.638972619-1.394225272-0.5414037020.5202014840.076319351-0.2391277260.084371343
SN: Slide Number; RN: Replicate Number; WN: Well Number
Experimental Data (Classification Assay):Fluid:
CG_NumberSlide No.ttest P-valueRatio 1Ratio 2Ratio 3
CG10804Slide4C0.0000.6270.6070.543
CG10804Slide4O0.0001.3681.3931.319
CG10804Slide4P0.0000.6880.7110.698
C=Fdex Chase; O=Surface TfR (Okt9); P=Fdex Pulse

Integrated Annotations for CG10804 :Gene Ontology Annoations: Biological Process
Biological Process - TermGO IDEvidence
neurotransmitter transportGO:0006836inferred from sequence or structural similarity with DAT
Gene Ontology Annoations: Cellular Component
Cellular Component - TermGO IDEvidence
integral to membraneGO:0016021inferred from electronic annotation with InterPro:IPR000175
Gene Ontology Annoations: Molecular Function
Molecular Function - TermGO IDEvidence
neurotransmitter:sodium symporter activityGO:0005328inferred from sequence or structural similarity with UniProtKB:Q08469
neurotransmitter transporter activity
Other annotations
DatabaseLink
FlyBaseClick here to see CG10804 in FlyBase
FLIGHTClick here to see CG10804 in FLIGHT(Compendium of Drosophila in vivo and in vitro RNAi screens)
BioGRIDClick here to see CG10804 in BioGRID (Interaction Summary)
Off-targetClick here for Off-target data for CG10804
Entrez GeneEntrez Gene page for CG10804
UniprotUniprot page for CG10804

Endosite Team :
Prof. Satyajit Mayor (Contact : mayor@ancbs.res.in)
Prof. R. Sowdhamini (Contact : mini@ncbs.res.in)